Buurman WA, Daemen AJ, van der Linden CJ, Kootstra G: Clinically used concentrations of cyclosporine A only partially inhibit interferon-gamma production by activated T lymphocytes. Transplant Proc. 1987, 19 (1 Pt 2): 1193-
CAS
PubMed
Google Scholar
Kahan BD: Cyclosporine. N Engl J Med. 1989, 321 (25): 1725-1738.
Article
CAS
PubMed
Google Scholar
Mason J: Pharmacology of cyclosporine (sandimmune). VII. Pathophysiology and toxicology of cyclosporine in humans and animals. Pharmacol Rev. 1990, 41 (3): 423-434.
CAS
PubMed
Google Scholar
Remuzzi G, Perico N: Cyclosporine-induced renal dysfunction in experimental animals and humans. Kidney Int Suppl. 1995, 52: S70-4.
CAS
PubMed
Google Scholar
Wolf A, Clemann N, Frieauff W, Ryffel B, Cordier A: Role of reactive oxygen formation in the cyclosporin-A-mediated impairment of renal functions. Transplant Proc. 1994, 26 (5): 2902-2907.
CAS
PubMed
Google Scholar
Ahmed SS, Napoli KL, Strobel HW: Oxygen radical formation during cytochrome P450-catalyzed cyclosporine metabolism in rat and human liver microsomes at varying hydrogen ion concentrations. Mol Cell Biochem. 1995, 151 (2): 131-140. 10.1007/BF01322335.
Article
CAS
PubMed
Google Scholar
Knight JA, Cheung AK, Pieper RK, Servilla K: Increased urinary lipoperoxide levels in renal transplant patients. Ann Clin Lab Sci. 1989, 19 (4): 238-241.
CAS
PubMed
Google Scholar
Inselmann G, Hannemann J, Baumann K: Cyclosporine A induced lipid peroxidation and influence on glucose-6-phosphatase in rat hepatic and renal microsomes. Res Commun Chem Pathol Pharmacol. 1990, 68 (2): 189-203.
CAS
PubMed
Google Scholar
Perez de Lema G, Arribas-Gomez I, Ruiz-Gines JA, de Arriba G, Prieto A, Rodriguez-Puyol D, Rodriguez-Puyol M: Reactive oxygen species mediate the effects of cyclosporine A on human cultured mesangial cells. Transplant Proc. 1997, 29 (1-2): 1241-1243. 10.1016/S0041-1345(96)00482-4.
Article
CAS
PubMed
Google Scholar
Wang C, Salahudeen AK: Lipid peroxidation accompanies cyclosporine nephrotoxicity: effects of vitamin E. Kidney Int. 1995, 47 (3): 927-934.
Article
CAS
PubMed
Google Scholar
Walker G, Kunz D, Pignat W, Wiesenberg I, Van den Bosch H, Pfeilschifter J: Tetranactin inhibits interleukin 1 beta and cAMP induction of group II phospholipase A2 in rat renal mesangial cells. Eur J Pharmacol. 1996, 306 (1-3): 265-270. 10.1016/0014-2999(96)00203-8.
Article
CAS
PubMed
Google Scholar
Longoni B, Giovannini L, Migliori M, Bertelli AA, Bertelli A: Cyclosporine-induced lipid peroxidation and propionyl carnitine protective effect. Int J Tissue React. 1999, 21 (1): 7-11.
CAS
PubMed
Google Scholar
Ammon HP, Wahl MA: Pharmacology of Curcuma longa. Planta Med. 1991, 57 (1): 1-7.
Article
CAS
PubMed
Google Scholar
Joe B, Lokesh BR: Effect of curcumin and capsaicin on arachidonic acid metabolism and lysosomal enzyme secretion by rat peritoneal macrophages. Lipids. 1997, 32 (11): 1173-1180.
Article
CAS
PubMed
Google Scholar
Satoskar RR, Shah SJ, Shenoy SG: Evaluation of anti-inflammatory property of curcumin (diferuloyl methane) in patients with postoperative inflammation. Int J Clin Pharmacol Ther Toxicol. 1986, 24 (12): 651-654.
CAS
PubMed
Google Scholar
Taher MM, Lammering G, Hershey C, Valerie K: Curcumin inhibits ultraviolet light induced human immunodeficiency virus gene expression. Mol Cell Biochem. 2003, 254 (1-2): 289-297. 10.1023/A:1027393719610.
Article
CAS
PubMed
Google Scholar
De Clercq E: Current lead natural products for the chemotherapy of human immunodeficiency virus (HIV) infection. Med Res Rev. 2000, 20 (5): 323-349. 10.1002/1098-1128(200009)20:5<323::AID-MED1>3.0.CO;2-A.
Article
CAS
PubMed
Google Scholar
Pal A, Pal AK: Studies on the genotoxicity of turmeric extracts in bacterial system. Int J Antimicrob Agents. 2000, 16 (4): 415-417. 10.1016/S0924-8579(00)00268-5.
Article
CAS
PubMed
Google Scholar
Jurgens TM, Frazier EG, Schaeffer JM, Jones TE, Zink DL, Borris RP, Nanakorn W, Beck HT, Balick MJ: Novel nematocidal agents from Curcuma comosa. J Nat Prod. 1994, 57 (2): 230-235. 10.1021/np50104a006.
Article
CAS
PubMed
Google Scholar
Biswas SK, McClure D, Jimenez LA, Megson IL, Rahman I: Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity. Antioxid Redox Signal. 2005, 7 (1-2): 32-41. 10.1089/ars.2005.7.32.
Article
CAS
PubMed
Google Scholar
Iqbal M, Sharma SD, Okazaki Y, Fujisawa M, Okada S: Dietary supplementation of curcumin enhances antioxidant and phase II metabolizing enzymes in ddY male mice: possible role in protection against chemical carcinogenesis and toxicity. Pharmacol Toxicol. 2003, 92 (1): 33-38. 10.1034/j.1600-0773.2003.920106.x.
Article
CAS
PubMed
Google Scholar
Balasubramanyam M, Koteswari AA, Kumar RS, Monickaraj SF, Maheswari JU, Mohan V: Curcumin-induced inhibition of cellular reactive oxygen species generation: novel therapeutic implications. J Biosci. 2003, 28 (6): 715-721.
Article
CAS
PubMed
Google Scholar
Vajragupta O, Boonchoong P, Watanabe H, Tohda M, Kummasud N, Sumanont Y: Manganese complexes of curcumin and its derivatives: evaluation for the radical scavenging ability and neuroprotective activity. Free Radic Biol Med. 2003, 35 (12): 1632-1644. 10.1016/j.freeradbiomed.2003.09.011.
Article
CAS
PubMed
Google Scholar
Sumanont Y, Murakami Y, Tohda M, Vajragupta O, Matsumoto K, Watanabe H: Evaluation of the nitric oxide radical scavenging activity of manganese complexes of curcumin and its derivative. Biol Pharm Bull. 2004, 27 (2): 170-173. 10.1248/bpb.27.170.
Article
CAS
PubMed
Google Scholar
Kim JE, Kim AR, Chung HY, Han SY, Kim BS, Choi JS: In vitro peroxynitrite scavenging activity of diarylheptanoids from Curcuma longa. Phytother Res. 2003, 17 (5): 481-484. 10.1002/ptr.1179.
Article
CAS
PubMed
Google Scholar
Das KC, Das CK: Curcumin (diferuloylmethane), a singlet oxygen ((1)O(2)) quencher. Biochem Biophys Res Commun. 2002, 295 (1): 62-66. 10.1016/S0006-291X(02)00633-2.
Article
CAS
PubMed
Google Scholar
Cheng CH, Hsieh CL, Shu KH, Chen YL, Chen HC: Effect of calcium channel antagonist diltiazem and calcium ionophore A23187 on cyclosporine A-induced apoptosis of renal tubular cells. FEBS Lett. 2002, 516 (1-3): 191-196. 10.1016/S0014-5793(02)02563-2.
Article
CAS
PubMed
Google Scholar
Mervaala EM, Pere AK, Lindgren L, Laakso J, Teravainen TL, Karjala K, Vapaatalo H, Ahonen J, Karppanen H: Effects of dietary sodium and magnesium on cyclosporin A-induced hypertension and nephrotoxicity in spontaneously hypertensive rats. Hypertension. 1997, 29 (3): 822-827.
Article
CAS
PubMed
Google Scholar
McGrath LT, Treacy R, McClean E, Brown JH: Oxidative stress in cyclosporin and azathioprine treated renal transplant patients. Clin Chim Acta. 1997, 264 (1): 1-12. 10.1016/S0009-8981(97)00088-0.
Article
CAS
PubMed
Google Scholar
Satyanarayana PS, Chopra K: Oxidative stress-mediated renal dysfunction by cyclosporine A in rats: attenuation by trimetazidine. Ren Fail. 2002, 24 (3): 259-274. 10.1081/JDI-120005360.
Article
CAS
PubMed
Google Scholar
De Nicola L, Thomson SC, Wead LM, Brown MR, Gabbai FB: Arginine feeding modifies cyclosporine nephrotoxicity in rats. J Clin Invest. 1993, 92 (4): 1859-1865.
Article
PubMed Central
CAS
PubMed
Google Scholar
Zhong Z, Arteel GE, Connor HD, Yin M, Frankenberg MV, Stachlewitz RF, Raleigh JA, Mason RP, Thurman RG: Cyclosporin A increases hypoxia and free radical production in rat kidneys: prevention by dietary glycine. Am J Physiol. 1998, 275 (4 Pt 2): F595-604.
CAS
PubMed
Google Scholar
Moss NG, Powell SL, Falk RJ: Intravenous cyclosporine activates afferent and efferent renal nerves and causes sodium retention in innervated kidneys in rats. Proc Natl Acad Sci U S A. 1985, 82 (23): 8222-8226.
Article
PubMed Central
CAS
PubMed
Google Scholar
Lanese DM, Falk SA, Conger JD: Sequential agonist activation and site-specific mediation of acute cyclosporine constriction in rat renal arterioles. Transplantation. 1994, 58 (12): 1371-1378.
CAS
PubMed
Google Scholar
Lanese DM, Conger JD: Effects of endothelin receptor antagonist on cyclosporine-induced vasoconstriction in isolated rat renal arterioles. J Clin Invest. 1993, 91 (5): 2144-2149.
Article
PubMed Central
CAS
PubMed
Google Scholar
Avdonin PV, Cottet-Maire F, Afanasjeva GV, Loktionova SA, Lhote P, Ruegg UT: Cyclosporine A up-regulates angiotensin II receptors and calcium responses in human vascular smooth muscle cells. Kidney Int. 1999, 55 (6): 2407-2414. 10.1046/j.1523-1755.1999.00481.x.
Article
CAS
PubMed
Google Scholar
Lo Russo A, Passaquin AC, Andre P, Skutella M, Ruegg UT: Effect of cyclosporin A and analogues on cytosolic calcium and vasoconstriction: possible lack of relationship to immunosuppressive activity. Br J Pharmacol. 1996, 118 (4): 885-892.
Article
PubMed Central
CAS
PubMed
Google Scholar
Zhong Z, Connor HD, Yin M, Moss N, Mason RP, Bunzendahl H, Forman DT, Thurman RG: Dietary glycine and renal denervation prevents cyclosporin A-induced hydroxyl radical production in rat kidney. Mol Pharmacol. 1999, 56 (3): 455-463.
CAS
PubMed
Google Scholar
Gottschalk AR, Boise LH, Thompson CB, Quintans J: Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2. Proc Natl Acad Sci USA. 1994, 91: 7350–7354-
Article
PubMed Central
PubMed
Google Scholar
Kitagaki K, Niwa S, Hoshiko K, Nagai H, Hayashi S, Totsuka T: Augmentation of apoptosis in bronchial exuded rat eosinophils by cyclosporin A. Biochem Biophys Res Commun. 1996, 222: 71-77. 10.1006/bbrc.1996.0715.
Article
CAS
PubMed
Google Scholar
Buttke TM, Sandstrom PA: Oxidative stress as a mediator of apoptosis. Immunol Today. 1994, 15: 7–10 -10.1016/0167-5699(94)90018-3.
Article
PubMed
Google Scholar
Ueda N, Shah SV: Endonuclease-induced DNA damage and cell death in oxidant injury to renal tubular epithelial cells. J Clin Invest. 1992, 90: 2593–2597-
PubMed Central
PubMed
Google Scholar
Shoskes DA: Effect of bioflavonoids quercetin and curcumin on ischemic renal injury: a new class of renoprotective agents. Transplantation. 1998, 66 (2): 147-152. 10.1097/00007890-199807270-00001.
Article
CAS
PubMed
Google Scholar
Skrzydlewska E, Ostrowska J, Farbiszewski R, Michalak K: Protective effect of green tea against lipid peroxidation in the rat liver, blood serum and the brain. Phytomedicine. 2002, 9 (3): 232-238. 10.1078/0944-7113-00119.
Article
CAS
PubMed
Google Scholar
Garcia-Cohen EC, Marin J, Diez-Picazo LD, Baena AB, Salaices M, Rodriguez-Martinez MA: Oxidative stress induced by tert-butyl hydroperoxide causes vasoconstriction in the aorta from hypertensive and aged rats: role of cyclooxygenase-2 isoform. J Pharmacol Exp Ther. 2000, 293 (1): 75-81.
CAS
PubMed
Google Scholar
Rukkumani R, Sri Balasubashini M, Menon VP: Protective effects of curcumin and photo-irradiated curcumin on circulatory lipids and lipid peroxidation products in alcohol and polyunsaturated fatty acid-induced toxicity. Phytother Res. 2003, 17 (8): 925-929. 10.1002/ptr.1254.
Article
CAS
PubMed
Google Scholar
Somasundaram S, Edmund NA, Moore DT, Small GW, Shi YY, Orlowski RZ: Dietary curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer. Cancer Res. 2002, 62 (13): 3868-3875.
CAS
PubMed
Google Scholar
Sreejayan, Rao MN: Curcuminoids as potent inhibitors of lipid peroxidation. J Pharm Pharmacol. 1994, 46 (12): 1013-1016.
Article
CAS
PubMed
Google Scholar
Reddy AC, Lokesh BR: Studies on the inhibitory effects of curcumin and eugenol on the formation of reactive oxygen species and the oxidation of ferrous iron. Mol Cell Biochem. 1994, 137 (1): 1-8. 10.1007/BF00926033.
Article
CAS
PubMed
Google Scholar
Sreejayan N, Rao MN: Free radical scavenging activity of curcuminoids. Arzneimittelforschung. 1996, 46 (2): 169-171.
CAS
PubMed
Google Scholar
Rao CV, Rivenson A, Simi B, Reddy BS: Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound. Cancer Res. 1995, 55 (2): 259-266.
CAS
PubMed
Google Scholar
Unnikrishnan MK, Rao MN: Curcumin inhibits nitrogen dioxide induced oxidation of hemoglobin. Mol Cell Biochem. 1995, 146 (1): 35-37. 10.1007/BF00926878.
Article
CAS
PubMed
Google Scholar
Sreejayan, Rao MN: Nitric oxide scavenging by curcuminoids. J Pharm Pharmacol. 1997, 49 (1): 105-107.
Article
CAS
PubMed
Google Scholar
Ruby AJ, Kuttan G, Babu KD, Rajasekharan KN, Kuttan R: Anti-tumour and antioxidant activity of natural curcuminoids. Cancer Lett. 1995, 94 (1): 79-83. 10.1016/0304-3835(95)03827-J.
Article
CAS
PubMed
Google Scholar
Priyadarsini KI, Maity DK, Naik GH, Kumar MS, Unnikrishnan MK, Satav JG, Mohan H: Role of phenolic O-H and methylene hydrogen on the free radical reactions and antioxidant activity of curcumin. Free Radic Biol Med. 2003, 35 (5): 475-484. 10.1016/S0891-5849(03)00325-3.
Article
CAS
PubMed
Google Scholar
Chen J, Wanming D, Zhang D, Liu Q, Kang J: Water-soluble antioxidants improve the antioxidant and anticancer activity of low concentrations of curcumin in human leukemia cells. Pharmazie. 2005, 60 (1): 57-61.
CAS
PubMed
Google Scholar
Thiyagarajan M, Sharma SS: Neuroprotective effect of curcumin in middle cerebral artery occlusion induced focal cerebral ischemia in rats. Life Sci. 2004, 74 (8): 969-985. 10.1016/j.lfs.2003.06.042.
Article
CAS
PubMed
Google Scholar
Stamler JS, Singel DJ, Loscalzo J: Biochemistry of nitric oxide and its redox-activated forms. Science. 1992, 258 (5090): 1898-1902.
Article
CAS
PubMed
Google Scholar
Rivas-Cabanero L, Rodriguez-Lopez AM, Martinez-Salgado C, Saura M, Lamas S, Lopez-Novoa JM: Gentamicin treatment increases mesangial cell nitric oxide production. Exp Nephrol. 1997, 5 (1): 23-30.
CAS
PubMed
Google Scholar
Dawson TM, Dawson VL, Snyder SH: A novel neuronal messenger molecule in brain: the free radical, nitric oxide. Ann Neurol. 1992, 32 (3): 297-311. 10.1002/ana.410320302.
Article
CAS
PubMed
Google Scholar
Amore A, Emancipator SN, Cirina P, Conti G, Ricotti E, Bagheri N, Coppo R: Nitric oxide mediates cyclosporine-induced apoptosis in cultured renal cells. Kidney Int. 2000, 57 (4): 1549-1559. 10.1046/j.1523-1755.2000.00999.x.
Article
CAS
PubMed
Google Scholar
Chan MM, Huang HI, Fenton MR, Fong D: In vivo inhibition of nitric oxide synthase gene expression by curcumin, a cancer preventive natural product with anti-inflammatory properties. Biochem Pharmacol. 1998, 55 (12): 1955-1962. 10.1016/S0006-2952(98)00114-2.
Article
CAS
PubMed
Google Scholar
Ohkawa H, Ohishi N, Yagi K: Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 1979, 95 (2): 351-358. 10.1016/0003-2697(79)90738-3.
Article
CAS
PubMed
Google Scholar
Jollow D, Mitchell L, Zampaglione N, Gillete J: Bromobenze induced liver necrosis: protective role of glutathione and evidence for 3,4-bromobenzenoxide as the hepatotoxic intermediate. Pharmacol. 1974, 11: 151-169.
Article
CAS
Google Scholar
Kono Y: Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase. Arch Biochem Biophys. 1978, 186: 189-195. 10.1016/0003-9861(78)90479-4.
Article
CAS
PubMed
Google Scholar
Claiborne A: Handbook of Methods for Oxygen Radical Reaserch. Edited by: Boca Raton FL. 1985, CRC Press, 283-284.
Google Scholar
Green LC, Wagner DA, Glogowski J, Skipper PL, Wishnok JS, Tannenbaum SR: Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Anal Biochem. 1982, 126 (1): 131-138. 10.1016/0003-2697(82)90118-X.
Article
CAS
PubMed
Google Scholar