Curcumin, a diferuloylmethane, attenuates cyclosporine-induced renal dysfunction and oxidative stress in rat kidneys

Table 2 Effect of CMN on cyclosporine-induced Nitrite levels

Variables	Control	CsA (20)	CMN(15)	CsA (20)+ CMN(5)	CsA (20)+ CMN(10)	CsA (20)+ CMN(15)
Serum Nitrite(μmol/ml)	62 ± 3.72	91.9 ± 50.6^a	60 ± 3.15^b	77 ± 4.55^a,b	69 ± 8.75^b	61 ± 3.05^b
Tissue nitrite(μmol/mg)	103.518 ± 2.73	190.656 ± 7.97^a	101.814 ± 2.27^b	174.704 ± 4.01^a,b	144.79 ± 3.01^a,b	116.912 ± 2.27^a,b

Values are expressed mean ± mean. a = Statistical significant at P < 0.05 as compared to control, b = Statistical significant at P < 0.05 as compared to Cyclosporine (CsA)