(A) Hematoxylin and Eosin-stained sections of Normal rat kidneys. (B) Kidney section of CsA treated rats showing tubular brush-border loss, interstitial oedema, Necrosis of epithelium and Hyaline Casts. (C) Kidney Section of CMN (15 mg/kg p.o) + CsA treated rats showing prevention of CsA induced alterations. (D) Kidney section of CMN (15 mg/kg p.o.) treated rats showing almost normal morphology.