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Receptor G protein coupling and the cytoskeleton

Authors: Christoforos Charalambous, Jürgen Zezula and Michael Freissmuth

Citation: BMC Pharmacology 2007 7(Suppl 2):A76

Content type: Meeting abstract Published on: 14 November 2007

This article is part of a Supplement: Volume 7 Supplement 2
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Use of human-derived cell lines for the investigation of dietary factors which affect DNA stability

Authors: Heike Winter, Bettina Grasl-Kraupp, Rolf Schulte-Hermann, Michael Grusch, Wolfgang Mikulits, Veronika Ehrlich and Siegfried Knasmüller

Citation: BMC Pharmacology 2007 7(Suppl 2):A74

Content type: Meeting abstract Published on: 14 November 2007

This article is part of a Supplement: Volume 7 Supplement 2
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The potential antimutagenic and antioxidant effects of Maillard reaction products used as "natural antibrowning" agents

Authors: Stefanie Reichhold, Karin Koschutnig and Karl-Heinz Wagner

Citation: BMC Pharmacology 2007 7(Suppl 2):A72

Content type: Meeting abstract Published on: 14 November 2007

This article is part of a Supplement: Volume 7 Supplement 2
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iNOS expression and levels of nitric oxide in a hepatocarcinogenesis model of p47-NADPH knockout mice

Authors: Constanze Freiler, Eveline Kainzbauer, Rolf Schulte-Hermann and Wolfram Parzefall

Citation: BMC Pharmacology 2007 7(Suppl 2):A68

Content type: Meeting abstract Published on: 14 November 2007

This article is part of a Supplement: Volume 7 Supplement 2
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Ion channels alteration in dilated cardiomyopathy in human heart

Authors: Viktoria Szűts, István Baczkó, Dalma Ménesi, Zoltán Varga-Orvos, János Zs Kelemen, László G Puskás, Zoltán Bódi, Lajos Csincsik, Nazamin Houshmand, Miklós Bitay, Miklós Csanády, Norbert Jost, László Virág, Julius Gy Papp and András Varró

Citation: BMC Pharmacology 2007 7(Suppl 2):A51

Content type: Meeting abstract Published on: 14 November 2007

This article is part of a Supplement: Volume 7 Supplement 2
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The role of cannabinoid CB₁ receptor agonists in gastric mucosal protection in rats and mice

Authors: Nashwan Shujaa, Zoltán S Zádori, Mahmoud Al-Khrasani, Susanna Fürst, Tibor Wenger and Klára Gyires

Citation: BMC Pharmacology 2007 7(Suppl 2):A47

Content type: Meeting abstract Published on: 14 November 2007

This article is part of a Supplement: Volume 7 Supplement 2
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14-Methoxy-metopon: a highly potent μ opioid agonist on rat vas deferens

Authors: Kornél P Király, Pál Riba, Tamás Friedmann, Mahmoud Al-Khrasani, Helmut Schmidhammer and Susanna Fürst

Citation: BMC Pharmacology 2007 7(Suppl 2):A45

Content type: Meeting abstract Published on: 14 November 2007

This article is part of a Supplement: Volume 7 Supplement 2
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Electrophysiological characteristics of heart ventricular papillary muscles from histidine decarboxylase knockout and wild-type mice: effects of rosiglitazone

Authors: Andrea Szebeni and Valéria Kecskeméti

Citation: BMC Pharmacology 2007 7(Suppl 2):A43

Content type: Meeting abstract Published on: 14 November 2007

This article is part of a Supplement: Volume 7 Supplement 2
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Exploring the heterogeneity of use-dependent sodium channel inhibitor drugs. I: Fast- vs. slow-inactivated state preference

Authors: Nora Lenkey, Robert Karoly, E Sylvester Vizi and Arpad Mike

Citation: BMC Pharmacology 2007 7(Suppl 2):A41

Content type: Meeting abstract Published on: 14 November 2007

This article is part of a Supplement: Volume 7 Supplement 2
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Changes in the action of morphine challenge following perinatal morphine exposure in rats

Authors: Melinda Sobor, Julia Timár, Susanna Gyarmati and Susanna Fürst

Citation: BMC Pharmacology 2007 7(Suppl 2):A39

Content type: Meeting abstract Published on: 14 November 2007

This article is part of a Supplement: Volume 7 Supplement 2
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Ionotropic neurotransmitter receptors: activation and allosteric modulation

Authors: Gábor Maksay and László Fodor

Citation: BMC Pharmacology 2007 7(Suppl 2):A37

Content type: Meeting abstract Published on: 14 November 2007

This article is part of a Supplement: Volume 7 Supplement 2
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P2 receptor-mediated modulation of noradrenaline release by electrical field stimulation and ischemic conditions in superfused rat hippocampus slices

Authors: Cecília Csölle, Attila Heinrich and Beáta Sperlágh

Citation: BMC Pharmacology 2007 7(Suppl 2):A35

Content type: Meeting abstract Published on: 14 November 2007

This article is part of a Supplement: Volume 7 Supplement 2
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The basic difference in the pharmacological spectrum between methamphetamine and its derivative, the enhancer substance (-)-deprenyl

Authors: Ildikó Miklya

Citation: BMC Pharmacology 2007 7(Suppl 2):A33

Content type: Meeting abstract Published on: 14 November 2007

This article is part of a Supplement: Volume 7 Supplement 2
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Pharmacokinetics and pharmacodynamics of the dual FII/FX inhibitor BIBT 986 in endotoxin-induced coagulation

Authors: Judith M Leitner, Bernd Jilma, Florian B Mayr, Francesco Cardona, Alexander O Spiel, Christa Firbas, Karin Rathgen, Hildegard Stähle, Uwe Schühly and Eva U Graefe-Mody

Citation: BMC Pharmacology 2007 7(Suppl 2):A29

Content type: Meeting abstract Published on: 14 November 2007

This article is part of a Supplement: Volume 7 Supplement 2
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Experiments to localize the site for the anxiogenic action of NPY mediated by Y₂ receptors in the mouse brain

Authors: Ramon O Tasan, Stefan Weger, Regine Heilbronn, Ngoc K Nguyen, Nicolas Singewald, Herbert Herzog and Günther Sperk

Citation: BMC Pharmacology 2007 7(Suppl 2):A14

Content type: Meeting abstract Published on: 14 November 2007

This article is part of a Supplement: Volume 7 Supplement 2
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Mapping the interaction sites of the viral encoded chemokine receptor US28 and the sorting protein GASP-1

Authors: Gerald P Parzmair, Wolfgang Platzer and Maria Waldhoer

Citation: BMC Pharmacology 2007 7(Suppl 2):A12

Content type: Meeting abstract Published on: 14 November 2007

This article is part of a Supplement: Volume 7 Supplement 2
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Anticonvulsant and neuroprotective actions of endogenous dynorphin

Authors: Christoph Schwarzer, Stephan Loacker, Eduard Schunk, Mohammad Sayyah and Herbert Herzog

Citation: BMC Pharmacology 2007 7(Suppl 2):A10

Content type: Meeting abstract Published on: 14 November 2007

This article is part of a Supplement: Volume 7 Supplement 2
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Selective serotonin reuptake inhibitors: a new modality for the treatment of lymphoma/leukaemia?

Authors: Christian Schuster, Nora Fernbach, Uwe Rix, Giulio Superti-Furga, Marion Holy, Michael Freissmuth, Harald H Sitte and Veronika Sexl

Citation: BMC Pharmacology 2007 7(Suppl 2):A8

Content type: Meeting abstract Published on: 14 November 2007

This article is part of a Supplement: Volume 7 Supplement 2
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Heterologous expression of membrane proteins in cardiac myocytes

Authors: Miroslav Radenkovic, Halyna Pankevych, Oliver Kudlacek, Ingrid Gsandtner and Karlheinz Hilber

Citation: BMC Pharmacology 2007 7(Suppl 2):A6

Content type: Meeting abstract Published on: 14 November 2007

This article is part of a Supplement: Volume 7 Supplement 2
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The hCMV chemokine receptor US28 prevents melanoma growth

Authors: Elisabeth Moser, Joshi Shripad, Ping Quan, Helmut Seidl, Sasa Frank, Zhao-Jun Liu, Mizuho Fukunaga, Ronan McDaid, Helmut Kerl, Meenhard Herlyn, Helmut Schaider and Maria Waldhoer

Citation: BMC Pharmacology 2007 7(Suppl 2):A4

Content type: Meeting abstract Published on: 14 November 2007

This article is part of a Supplement: Volume 7 Supplement 2
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Restricted expression between parvalbumin and substance P receptor NK₁ in interneurones of the lateral amygdala

Authors: Hari Kishore Sreepathi and Francesco Ferraguti

Citation: BMC Pharmacology 2007 7(Suppl 2):A2

Content type: Meeting abstract Published on: 14 November 2007

This article is part of a Supplement: Volume 7 Supplement 2
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Tuberous sclerosis preclinical studies: timing of treatment, combination of a rapamycin analog (CCI-779) and interferon-gamma, and comparison of rapamycin to CCI-779

Tuberous Sclerosis Complex (TSC) is an autosomal dominant hamartoma disorder with variable expression for which treatment options are limited. TSC is caused by a mutation in either the TSC1 or TSC2 genes, whose p...

Authors: Michael P Messina, Aubrey Rauktys, Laifong Lee and Sandra L Dabora

Citation: BMC Pharmacology 2007 7:14

Content type: Research article Published on: 6 November 2007
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Impact of imatinib on the pharmacokinetics and in vivo efficacy of etoposide and/or ifosfamide

Using a human small cell lung cancer (SCLC) xenografted in nude mice, we have previously reported enhanced tumor growth inhibition following chemotherapy in combination with imatinib (STI571). We therefore invest...

Authors: Keyvan Rezaï, François Lokiec, Isabelle Grandjean, Sophie Weill, Patricia de Cremoux, Vincent Bordier, Richard Ekue, Mickael Garcia, Marie-France Poupon and Didier Decaudin

Citation: BMC Pharmacology 2007 7:13

Content type: Research article Published on: 27 October 2007
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Ciclesonide uptake and metabolism in human alveolar type II epithelial cells (A549)

Ciclesonide is a novel inhaled corticosteroid for the treatment of airway inflammation. In this study we investigated uptake and in vitro metabolism of ciclesonide in human alveolar type II epithelial cells (A549...

Authors: Takashi Nonaka, Rüdiger Nave, Nigel McCracken, Atsuko Kawashimo and Yasuhiro Katsuura

Citation: BMC Pharmacology 2007 7:12

Content type: Research article Published on: 27 September 2007
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Gene expression profiling reveals effects of Cimicifuga racemosa (L.) NUTT. (black cohosh) on the estrogen receptor positive human breast cancer cell line MCF-7

Extracts from the rhizome of Cimicifuga racemosa (black cohosh) are increasingly popular as herbal alternative to hormone replacement therapy (HRT) for the alleviation of postmenopausal disorders. However, the mo...

Authors: Friedemann Gaube, Stefan Wolfl, Larissa Pusch, Torsten C Kroll and Matthias Hamburger

Citation: BMC Pharmacology 2007 7:11

Content type: Research article Published on: 20 September 2007
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An integrative in silico approach for discovering candidates for drug-targetable protein-protein interactions in interactome data

Protein-protein interactions (PPIs) are challenging but attractive targets for small chemical drugs. Whole PPIs, called the 'interactome', have been emerged in several organisms, including human, based on the ...

Authors: Nobuyoshi Sugaya, Kazuyoshi Ikeda, Toshiyuki Tashiro, Shizu Takeda, Jun Otomo, Yoshiko Ishida, Akiko Shiratori, Atsushi Toyoda, Hideki Noguchi, Tadayuki Takeda, Satoru Kuhara, Yoshiyuki Sakaki and Takao Iwayanagi

Citation: BMC Pharmacology 2007 7:10

Content type: Research article Published on: 20 August 2007
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Sodium valproate stimulates potassium and chloride urinary excretion in rats: gender differences

The diuretic effect of valproates and its relation to urinary potassium (K⁺) and chloride (Cl^-) excretion have not yet been investigated, so the aim of this study was to evaluate the influence of a single dose of...

Authors: Eitautė Jakutiene, Jurgita Grikiniene, Arunas Vaitkevicius, Marina Tschaika, Janina Didziapetriene and Donatas Stakisaitis

Citation: BMC Pharmacology 2007 7:9

Content type: Research article Published on: 6 August 2007
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Activation of the cGMP/cGKI signalling pathway in primary murine VSMCs accelerates growth

Authors: Pascal Weinmeister, Robert Lukowski, Claudia Claudia Traidl-Hoffmann, Stefan Linder, Franz Hofmann and Robert Feil

Citation: BMC Pharmacology 2007 7(Suppl 1):P64

Content type: Poster presentation Published on: 25 July 2007

This article is part of a Supplement: Volume 7 Supplement 1
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Analysis of cGKI inhibition by Rp-cGMP analogs

Authors: Nadejda Valtcheva, Pascal Weinmeister, Franz Hofmann, Susanne Feil and Robert Feil

Citation: BMC Pharmacology 2007 7(Suppl 1):P62

Content type: Poster presentation Published on: 25 July 2007

This article is part of a Supplement: Volume 7 Supplement 1
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Targeting the NO – cGMP pathway: phenotyping of NO-insensitive sGCbeta1 H105F knockin mice

Authors: Robrecht Thoonen, Emmanuel Buys, Patrick Sips, Sofie Nimmegeers, Maureen Van den Hemel, Tino Hochepied, Johan Van de Voorde and Peter Brouckaert

Citation: BMC Pharmacology 2007 7(Suppl 1):P60

Content type: Poster presentation Published on: 25 July 2007

This article is part of a Supplement: Volume 7 Supplement 1
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cGMP-dependent protein kinase regulates Rap1 signaling in platelets

Authors: Albert Smolenski, Meike Hoffmeister, Pavel Riha, Olga Neumüller, Oliver Danielewski and Jan Schultess

Citation: BMC Pharmacology 2007 7(Suppl 1):P56

Content type: Poster presentation Published on: 25 July 2007

This article is part of a Supplement: Volume 7 Supplement 1
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Abstract withdrawn

Authors:

Citation: BMC Pharmacology 2007 7(Suppl 1):P54

Content type: Poster presentation Published on: 25 July 2007

This article is part of a Supplement: Volume 7 Supplement 1
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Cysteine-rich protein 2 is a downstream effector of cGMP-dependent protein kinase I in nociception

Authors: Achim Schmidtko, Wei Gao, Matthias Sausbier, Inga Grundei, Ellen Niederberger, Klaus Scholich, Andrea Huber, Hans-Dieter Allescher, Franz Hofmann, Peter Ruth and Gerd Geisslinger

Citation: BMC Pharmacology 2007 7(Suppl 1):P52

Content type: Poster presentation Published on: 25 July 2007

This article is part of a Supplement: Volume 7 Supplement 1
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Increased aggregation of platelets lacking cGKI/PKG

Authors: Steffen Massberg, Matthias Sausbier, Matthias Werner, Jens Schlossmann and Franz Hofmann

Citation: BMC Pharmacology 2007 7(Suppl 1):S51

Content type: Oral presentation Published on: 25 July 2007

This article is part of a Supplement: Volume 7 Supplement 1
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The use of PDE5 inhibitors in the treatment of benign prostate hyperplasia and lower urinary tract symptoms: preclinical evidences

Authors: Peter Sandner, Hanna Tinel, Beatrix Stelte-Ludwig, Erwin Bischoff and Joachim Huetter

Citation: BMC Pharmacology 2007 7(Suppl 1):P48

Content type: Poster presentation Published on: 25 July 2007

This article is part of a Supplement: Volume 7 Supplement 1
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Novel GKAPs for cGMP-dependent protein kinase type II: identification and functional significance

Authors: Boris M Hogema and Hugo R de Jonge

Citation: BMC Pharmacology 2007 7(Suppl 1):S45

Content type: Oral presentation Published on: 25 July 2007

This article is part of a Supplement: Volume 7 Supplement 1
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NO-sensitive guanylyl cyclase β1 subunit interacts with chromosomes during mitosis: novel role in the regulation of chromatin condensation

Authors: Paula Pifarré, María Antonia Baltrons, Verónca Davalos, Simon Schwartz Jr and Agustina García

Citation: BMC Pharmacology 2007 7(Suppl 1):S43

Content type: Oral presentation Published on: 25 July 2007

This article is part of a Supplement: Volume 7 Supplement 1
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Vascular remodelling in the absence and presence of cGKI

Authors: Robert Lukowski, Dominik Bernhard, Pascal Weinmeister, Susanne Feil, Michael Gotthardt, Joachim Herz, Stefan Massberg, Franz Hofmann and Robert Feil

Citation: BMC Pharmacology 2007 7(Suppl 1):S41

Content type: Oral presentation Published on: 25 July 2007

This article is part of a Supplement: Volume 7 Supplement 1
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A new Rac-cGMP signaling pathway

Authors: Xin-Yun Huang

Citation: BMC Pharmacology 2007 7(Suppl 1):S39

Content type: Oral presentation Published on: 25 July 2007

This article is part of a Supplement: Volume 7 Supplement 1
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Structural insights into sGC

Authors: Xiaolei Ma, Nazish Sayed, Annie Beuve and Focco van den Akker

Citation: BMC Pharmacology 2007 7(Suppl 1):S37

Content type: Oral presentation Published on: 25 July 2007

This article is part of a Supplement: Volume 7 Supplement 1
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Design and synthesis of the first NO- and haem-independent sGC activator BAY 58–2667 for the treatment of acute decompensated heart failure

Authors: Michael G Hahn, Cristina Alonso-Alija, Friederike Stoll, Markus Heil, Joachim Mittendorf, Karl-Heinz Schlemmer, Frank Wunder and Johannes-Peter Stasch

Citation: BMC Pharmacology 2007 7(Suppl 1):P25

Content type: Poster presentation Published on: 25 July 2007

This article is part of a Supplement: Volume 7 Supplement 1
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Interstitial cells of Cajal in the urethra as effectors of the nitric oxide action through the cyclic GMP pathway

Authors: Angeles Garcia-Pascual, Maria Sancho, Gonzalo Costa and Domingo Triguero

Citation: BMC Pharmacology 2007 7(Suppl 1):P23

Content type: Poster presentation Published on: 25 July 2007

This article is part of a Supplement: Volume 7 Supplement 1
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BAY 58–2667, a soluble guanylate cyclase activator, has a favourable safety profile and reduces peripheral vascular resistance in healthy male volunteers

Authors: Reiner Frey, Wolfgang Mück, Sigrun Unger, Ulrike Artmeier-Brandt, Gerrit Weimann and Georg Wensing

Citation: BMC Pharmacology 2007 7(Suppl 1):P21

Content type: Poster presentation Published on: 25 July 2007

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NO-induced motility effects in gastric fundus and pylorus of sGCβ1his105phe mutant mice

Authors: Ingeborg Dhaese, Gwen Vanneste, Robrecht Thoonen, Peter Brouckaert and Romain Lefebvre

Citation: BMC Pharmacology 2007 7(Suppl 1):P15

Content type: Poster presentation Published on: 25 July 2007

This article is part of a Supplement: Volume 7 Supplement 1
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The NO-cGMP axis in endothelial ischemia and ischemic preconditioning

Authors: Tommaso Gori and John Parker

Citation: BMC Pharmacology 2007 7(Suppl 1):S12

Content type: Oral presentation Published on: 25 July 2007

This article is part of a Supplement: Volume 7 Supplement 1
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Molecular modulators of cardiac stress targeted by PDE5 inhibition

Authors: Eiki Takimoto, Takayoshi Nagayama, Susan Vahebi, Carlo Gabrielli Tocchetti, Elizabeth Ketner, Diego Belardi, Hunter Champion, Michael Mendelsohn and David A Kass

Citation: BMC Pharmacology 2007 7(Suppl 1):S6

Content type: Oral presentation Published on: 25 July 2007

This article is part of a Supplement: Volume 7 Supplement 1
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Daily treatment with sildenafil, an inhibitor of cGMP-dependent phosphodiesterase, normalizes the exaggerated hemodynamic response to norepinephrine in fructose-fed rats

Authors: Delphine Behr-Roussel, Alexandra Oudot, Sandrine Compagnie, Diana Gorny, Olivier Le Coz, Jaques Bernabé, Chris Wayman, Laurent Alexandre and Francois Giuliano

Citation: BMC Pharmacology 2007 7(Suppl 1):P5

Content type: Poster presentation Published on: 25 July 2007

This article is part of a Supplement: Volume 7 Supplement 1
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LPS-induced down-regulation of NO-sensitive guanylyl cyclase in astrocytes occurs by proteasomal degradation in nuclear bodies

Authors: María Antonia Baltrons, Paula Pifarré, María Teresa Berciano, Miguel Lafarga and Agustina García

Citation: BMC Pharmacology 2007 7(Suppl 1):P3

Content type: Poster presentation Published on: 25 July 2007

This article is part of a Supplement: Volume 7 Supplement 1
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Therapeutic potential of soluble guanylate cyclase agonists in pulmonary hypertension

Authors: Oleg V Evgenov, Daniel S Kohane and Warren M Zapol

Citation: BMC Pharmacology 2007 7(Suppl 1):S2

Content type: Oral presentation Published on: 25 July 2007

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cGMP signaling pathway is involved in Leyding cell stress response

Authors: Silvana Andric, Natasa Stojkov, Marija Janjic, Stanko Stojilkovic and Tatjana Kostic

Citation: BMC Pharmacology 2007 7(Suppl 1):P1

Content type: Poster presentation Published on: 25 July 2007

This article is part of a Supplement: Volume 7 Supplement 1
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