Background
Reduced ocular perfusion is related to several common eye diseases, like age-related macular degeneration, diabetic retinopathy or glaucoma. Moxaverine, a phosphodiesterase inhibitor, has a vasodilating effect on peripheral vessels and is therefore clinically used to increase blood flow. It was recently shown that a dose of 150 mg moxaverine administered intravenously increases retinal blood flow in healthy subjects and in patients with ocular diseases. The aim of this study was to investigate the effect of oral moxaverine on ocular blood flow.