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Table 1 Comparison of Human, Pig, and Minipig CYP N-terminal sequences

From: Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs

Gene Sequence (amino acid No.)
  1 10 20
Minipig CYP2A M L A S G L L L V A L L T/L R L X I F V L
Human CYP2A6a M L A S G M L L V A L L V C L T V M V L
  1 10 18
Minipig CYP2C M D V L V X L A L X L L L V X L L L
Human CYP2C9b M D S L V V L V L C L S C L LL L S
  1 10 20
Minipig CYP3A M D L I P G F S T E T W V L L A T S L V
Pig CYP3A29c M D L I P G F S T E T W V L L A T S L V
Human CYP3Ad M A L I P D L A M E T R L L L A V S L V
  1. Notes: X – amino acid was not identified. Similarities between pig and minipig cDNAs in bold. GeneBank accession numbers: aAF182275, bM61855, cZ93099, dAF209389