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Figure 3 | BMC Pharmacology

Figure 3

From: A covalent peptide inhibitor of RGS4 identified in a focused one-bead, one compound library screen

Figure 3

Irreversibility experiments. RGS-biotin on avidin beads was treated with 5nd (100 μM) or 5nm (100 μM) and then washed in buffer (with or without 1 mM DTT) or not washed and put in the FCPIA using RGS4 (A) or RGS8 (B) (mean ± S.E.M., n ≥ 2) *p < 0.05, **p < 0.01, ***p < 0.001 compared to no peptide (100%); #p < 0.05, ##p < 0.01, ###p < 0.001 compared to 5nd no wash.

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