Figure 3

CRE-SPAP production in forskolin-stimulated CHO-H3-SPAP cells in response to a) N-α-methylhistamine, b) immepip c) imetit and d) S-α-methylhistamine in the absence and presence of 30 nM, 300 nM or 3000 nM conessine. Bars show basal CRE-SPAP production and that in response to 4 μM forskolin alone, and 30 nM, 300 nM or 3000 nM conessine in the presence of 4 μM forskolin. Data points are mean ± s.e.m. of triplicate values from a single experiment and are representative of 4 separate experiments in each case.