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Table 1 10% and 50% effective concentrations (EC) for cytotoxicity in ZFL cells.

From: Comparison of four different colorimetric and fluorometric cytotoxicity assays in a zebrafish liver cell line

 

Tamoxifen

4-OH-Tamoxifen

Flusilazole

 

EC10 [μM]

EC50 [μM]

EC10 [μM]

EC50 [μM]

EC10 [μM]

EC50 [μM]

LDH

0.61 ± 0.67

1.88 ± 1.01

0.73 ± 0.55

1.62 ± 0.01

2.28 ± 3.12

17.37 ± 14.53

MTT

1.39 ± 0.77

3.46 ± 0.70

1.49 ± 0.82

1.78 ± 0.40

11.29 ± 5.88

18.37 ± 14.11

AB

1.37 ± 0.33

3.12 ± 0.25

0.79 ± 0.40

1.17 ± 0.24

16.13 ± 11.44

26.40 ± 7.30

CFDA-AM

2.52 ± 2.14

3.35 ± 0.75

1.08 ± 0.62

1.73 ± 0.67

6.49 ± 1.08

16.68 ± 4.76

  1. Effective concentrations (EC) causing 10 or 50% loss of cell viability were determined from a four parameter logistic equation fitted to the experimental data for three individual experiments. EC values shown in the table are mean values from three experiments ± standard deviation. No EC values could be determined for BaP since dose-response curves were incomplete (highest concentrations which were already above aqueous solubility caused 37% loss in cell viability at most). EC values were not significantly different from each other (One way ANOVA, Tukey's test, p < 0.05).