| Tamoxifen | 4-OH-Tamoxifen | Flusilazole |
---|
| EC10 [μM] | EC50 [μM] | EC10 [μM] | EC50 [μM] | EC10 [μM] | EC50 [μM] |
---|
LDH | 0.61 ± 0.67 | 1.88 ± 1.01 | 0.73 ± 0.55 | 1.62 ± 0.01 | 2.28 ± 3.12 | 17.37 ± 14.53 |
MTT | 1.39 ± 0.77 | 3.46 ± 0.70 | 1.49 ± 0.82 | 1.78 ± 0.40 | 11.29 ± 5.88 | 18.37 ± 14.11 |
AB | 1.37 ± 0.33 | 3.12 ± 0.25 | 0.79 ± 0.40 | 1.17 ± 0.24 | 16.13 ± 11.44 | 26.40 ± 7.30 |
CFDA-AM | 2.52 ± 2.14 | 3.35 ± 0.75 | 1.08 ± 0.62 | 1.73 ± 0.67 | 6.49 ± 1.08 | 16.68 ± 4.76 |
- Effective concentrations (EC) causing 10 or 50% loss of cell viability were determined from a four parameter logistic equation fitted to the experimental data for three individual experiments. EC values shown in the table are mean values from three experiments ± standard deviation. No EC values could be determined for BaP since dose-response curves were incomplete (highest concentrations which were already above aqueous solubility caused 37% loss in cell viability at most). EC values were not significantly different from each other (One way ANOVA, Tukey's test, p < 0.05).