Table 1 IC₅₀ values of substituted trans-stilbenes as inhibitors of the TPA-induced activation of AP-1

1

0.8 ± 0.05

+

+

8

0.7 ± 0.04

-

-

9

2.4 ± 0.7

-

-

10

3.8 ± 1.1

-

-

11

1.3 ± 0.03

-

+

29

1.1 ± 0.1

+

+

30

0.8 ± 0.1

-

+

31

1.6 ± 0.6

-

+

46

0.5 ± 0.1

-

-

47

0.8 ± 0.1

-

-

48

0.8 ± 0.03

-

-

49

1.0 ± 0.12

-

-

50

0.8 ± 0.15

-

-

62

2.5 ± 0.5

-

-

63

2.1 ± 0.4

-

-