Figure 1From: Substituted trans-stilbenes can inhibit or enhance the TPA-induced up-regulation of activator protein-1Inhibition or enhancement of the TPA-induced activation of AP-1 by resveratrol and phenolic trans -stilbenes. Screening with the 293T/AP-1-luc cell for the effects of resveratrol and phenolic trans-stilbenes on TPA-induced activation of AP-1 demonstrated that resveratrol and 7 were enhancers, 1, 2, 3 and 4 were inhibitors, and 5 and 6 were inactive. These phenolic compounds retain anti-oxidant activity. Each value represents the average of triplicate points. Error bars show standard deviations. The * notation indicates p < 0.01.Back to article page