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Table 2 Effect of Atorvastatin and Pitavastatin on L-Methionine induced changes in Serum homocysteine.

From: Ameliorative role of Atorvastatin and Pitavastatin in L-Methionine induced vascular dementia in rats

Groups Treatment Dose (kg/day, p.o.) Serum homocysteine (μM)
I Control 10 ml(0.5%w/w CMC) 4.23 ± 0.15
II L-Methionine 1.7 g 20.8 ± 0.84a
III Atorvastatin per se 10 mg 3.95 ± 0.21
IV Pitavastatin per se 10 mg 3.92 ± 0.23
V L-Methionine + Atorvastatin 10 mg 12.9 ± 0.38b
VI L-Methionine + Pitavastatin 10 mg 13.5 ± 0.34b
  1. Each group (n = 10), represent mean ± SEM.
  2. a = p < 0.01 Vs serum homocysteine level of Control.
  3. b = p < 0.05 Vs serum homocysteine level of L-Methionine treated group.