Table 2 Effect of Atorvastatin and Pitavastatin on L-Methionine induced changes in Serum homocysteine.
From: Ameliorative role of Atorvastatin and Pitavastatin in L-Methionine induced vascular dementia in rats
Groups | Treatment | Dose (kg/day, p.o.) | Serum homocysteine (μM) |
|---|---|---|---|
I | Control | 10 ml(0.5%w/w CMC) | 4.23 ± 0.15 |
II | L-Methionine | 1.7 g | 20.8 ± 0.84a |
III | Atorvastatin per se | 10 mg | 3.95 ± 0.21 |
IV | Pitavastatin per se | 10 mg | 3.92 ± 0.23 |
V | L-Methionine + Atorvastatin | 10 mg | 12.9 ± 0.38b |
VI | L-Methionine + Pitavastatin | 10 mg | 13.5 ± 0.34b |