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Table 3 Concentration of hydrogen peroxide and lipid peroxidation products in the liver of pigs fed a control diet or a diet supplemented with 5 g clofibrate per kg for 28 days

From: Clofibrate treatment in pigs: Effects on parameters critical with respect to peroxisome proliferator-induced hepatocarcinogenesis in rodents

Treatment

Control (n = 9)

Clofibrate (n = 9)

Hydrogen peroxide (fluorescence/g liver)

29,437 ± 8,361

20,078 ± 7,225*

Thiobarbituric acid-reactive substances

  

   (nmol/g liver)

7.2 ± 1.6

7.7 ± 2.7

   [nmol/(mmol triglycerides + cholesterol)]

1.15 ± 0.26

1.20 ± 0.42

Conjugated dienes (nmol/g)

  

   (nmol/g liver)

16 ± 2

16 ± 2

   [nmol/(mmol triglycerides + cholesterol)]

2.56 ± 0.32

2.49 ± 0.31

  1. Results are means ± SD.
  2. *Significantly different from control group (P < 0.05)