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Table 3 Summary of results from the three analyses for the bait-prey pairs

From: An integrative in silico approach for discovering candidates for drug-targetable protein-protein interactions in interactome data

 

bait-prey

# of unique pairs

770

# of pairs in which both fragments have domains

734

   # of pairs in which a domain pair has been already known or predicted as interacting partner

23

   # of pairs in which both fragments have a single domain

62

   # of pairs satisfying one or both criteria for domain detection above

83

# of pairs in which one or both fragments have nearly identical tertiary structures

211

   # of pairs in which one or both fragments have pockets

203

# of pairs with identical GO terms in any of the three categories

696

   cellular component

603 (264)*

   molecular function

647 (181)*

   biological process

594 (256)*

   # of pairs with statistically significant (P < 0.05) similarity scores for GO-term assignment in two out of the three GO categories

201

  1. * Numbers of pairs with statistically significant (P < 0.05) similarity scores are shown in parentheses.