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Figure 6 | BMC Pharmacology

Figure 6

From: Inhibition of p38 mitogen-activated protein kinase enhances c-Jun N-terminal kinase activity: Implication in inducible nitric oxide synthase expression

Figure 6

Effect of SB220025 on JNK activation. Cells were stimulated with LPS 1 h before addition of SB220025. Incubations were terminated at the indicated time points and parallel immunoblots were run from same cell lysates using antibodies against Thr183/Tyr185 phosphorylated JNK (pp54 and pp46), total JNK (p54 and p46). Phosphorylated JNK values were normalised to total JNK values. Results are expressed as mean ± S.E.M. (n = 3). *P < 0.05, ***P < 0.001 compared with cells treated with LPS only.

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BMC Pharmacology

ISSN: 1471-2210