Figure 3
From: Dibenzazecine compounds with a novel dopamine/5HT2A receptor profile and 3D-QSAR analysis
Heterologous competition binding curves of LE404 (■) and LE410 (●) at hD 1 (A), hD 2L (B), and 5HT 2A (C) receptors. Data shown are the means ± SEM of specific binding of at least four determinations assayed in triplicate. A. 0.2 nM [3H]SCH23390 was used for hD1 receptors. Nonspecific binding was determined with 1 μM LE300. B. 0.1 nM [3H]spiperone was used for hD2L receptors. Nonspecific binding was determined with 1 μM haloperidol. C. 0.1 nM [3H]spiperone was used for h5HT2A receptors. Nonspecific binding was determined with 1 μM ketanserin.