Figure 6
Sensitivities to the barbiturate pentobarbital and the benzodizepine flurazepam. Modulation of GABA-induced currents by pentobarbital and flurazepam in recombinant GABAA receptors expressed in Xenopus oocytes. A. Pentobarbital dose-response curves in the presence of EC25 GABA (set to 100 %). The values are means ± standard errors (n = 6 for α3β1; n = 9 for α3β1γ2; n = 4 for α3β1θ and n = 8 for α3β1ε receptors). B. Flurazepam dose-response curves in the presence of EC25 GABA (set to 100 %). The values are means ± standard errors (n = 6 for α3β1; n = 9 for α3β1γ2; n = 4 for α3β1θ and n = 8 for α3β1ε receptors).