Figure 4
Sensitivities to the anesthetic propofol. Modulation of GABA-induced currents by propofol in recombinant GABAA receptors expressed in Xenopus oocytes. A. Representative traces of propofol (Prop, μM) modulation of GABA-induced currents (G, EC25 in μM) in different receptor subtypes. B. Propofol dose-response curves in the presence of EC25 GABA (set to 100 %). The values are means ± standard errors (n = 6 for α3β1; n = 9 for α3β1γ2; n = 6 for α3β1θ; n = 7 for α3β1ε and n = 3 for α3β1θε receptors).