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Table 1 Cardiac function at baseline and 7 h after endotoxin-challenge in WT and TG mice

From: Myocyte-specific overexpression of NOS3 prevents endotoxin-induced myocardial dysfunction in mice

  

dP/dtmax (mmHg/s)

CO (mL/min)

PMXEDV (mmHg/s)

dP/dtmax/IP (s-1)

Ees (mmHg/μL)

WT

baseline

15124 ± 1087

14.5 ± 1.9

50 ± 3

287 ± 12

11 ± 2

 

7h endotoxin

10024 ± 609*

6.1 ± 0.9*

31 ± 5*

161 ± 18*

3 ± 1*

TG

baseline

14562 ± 1491

15.6 ± 2.7

43 ± 2

255 ± 16

11 ± 4

 

7h endotoxin

15354 ± 495#

15.7 ± 0.7#

52 ± 5

228 ± 9

12 ± 2#

  1. *P < 0.05 vs baseline, #P < 0.05 vs WT