Table 2 Baseline model parameters The parameters chosen as those producing representative baseline (pre-drug) cardiovascular variables (Table 1). The co-efficient of variation (CV (%)) of these parameter values as determined by the Monte-Carlo sensitivity analysis is also shown.
Parameter | Name | Value | Units | CV (%) |
|---|---|---|---|---|
CPLv | Venous compliance | 0.45 | L mmHg-1 | 12.7 |
CPLratio | Ratio of venous over arterial compliance | 20 | dimensionless | 17.7 |
Vblood | Blood volume | 3.5 | L | 17.9 |
SVR | Systemic vascular resistance | 17 | RU | 5.5 |
MAPset | Mean arterial pressure set point | 100 | mmHg | 4.2 |
HRgain | Gain for heart rate control | 1.8 | bpma mmHg-1 | 23.6 |
CNT | Contractility | 3000 | mmHg sec-1 | 4.9 |