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Table 2 Effect of intravenous administration of oxybutynin on cystometrographic parameters in conscious obstructed rats

From: Urodynamic effects of oxybutynin and tolterodine in conscious and anesthetized rats under different cystometrographic conditions

  BVC (ml) MV (ml) NVC: frequency (N°/2 min) NVC: amplitude (mmHg)
Controls     
Before 1.27 ± 0.16 1.36 ± 0.24 5.3 ± 0.9 5.2 ± 0.9
After 1.14 ± 0.25 1.32 ± 0.30 4.9 ± 0.9 4.9 ± 0.9
Oxybutynin 0.3 mg/kg     
Before 1.98 ± 0.12 2.02 ± 0.46 5.9 ± 0.4 11.7 ± 1.8
After 2.58 ± 0.70 2.77 ± 0.50 5.5 ± 0.6 9.7 ± 2.1
  1. Data are expressed as mean ± s.e. mean. BVC: bladder volume capacity; MV: micturition volume; NVC: non-voiding contractions. * = p < 0.05; ** = p < 0.01 before vs after administration (Student's t test).