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Table 2 Effect of intravenous administration of oxybutynin on cystometrographic parameters in conscious obstructed rats

From: Urodynamic effects of oxybutynin and tolterodine in conscious and anesthetized rats under different cystometrographic conditions

 

BVC (ml)

MV (ml)

NVC: frequency (N°/2 min)

NVC: amplitude (mmHg)

Controls

    

Before

1.27 ± 0.16

1.36 ± 0.24

5.3 ± 0.9

5.2 ± 0.9

After

1.14 ± 0.25

1.32 ± 0.30

4.9 ± 0.9

4.9 ± 0.9

Oxybutynin 0.3 mg/kg

    

Before

1.98 ± 0.12

2.02 ± 0.46

5.9 ± 0.4

11.7 ± 1.8

After

2.58 ± 0.70

2.77 ± 0.50

5.5 ± 0.6

9.7 ± 2.1

  1. Data are expressed as mean ± s.e. mean. BVC: bladder volume capacity; MV: micturition volume; NVC: non-voiding contractions. * = p < 0.05; ** = p < 0.01 before vs after administration (Student's t test).
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BMC Pharmacology

ISSN: 1471-2210