Effect of oral administration of oxybutynin on BVC and MP in conscious rats under cystometry at different infusion rates. Data represent the mean (± S.E.) AUC change of BVC and MP calculated as reported in the Method Section. Oxybutynin was administered at 1 mg/kg (n = 9). Corresponding open bars represent changes recorded in the vehicle groups (n = 8). Infusion rates utilized were 0.025 and 0.05 ml/min. Rats were utilized 1 day after catheter implantation. Statistical significance was evaluated by Student's t test.