Table 4 The time- response relations between different anticancer drugs for cyto-toxic effects against leukemia cell line HL-60; N = 3, probimane, Pro; 5-fluorouracil, 5-Fu; doxorubicin, Dox; vincristine, VCR; ICRF-187, (+) stereo-isomer of razoxane
Compounds | Concentrations | Percentage inhibition % | ||
|---|---|---|---|---|
|  | μM | 24 h | 48 h | 72 h |
Pro | 10 | 75.6 | 78.5 | 75.9 |
5-Fu | 2 | 65.8 | 53.5 | 51.1 |
Dox | 4 | 78.3 | 72.4 | 72.3 |
VCR | 2 | 65.4 | 59.0 | 57.1 |
ICRF-187 | 10 | 47.6 | 37.8 | 42.9 |
MST-16 | 10 | 47.8 | 5.6 | 0.0 |