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Figure 1 | BMC Pharmacology

Figure 1

From: Sildenafil citrate increases myocardial cGMP content in rat heart, decreases its hypertrophic response to isoproterenol and decreases myocardial leak of creatine kinase and troponin T

Figure 1

Kaplan-Meier analysis of 10 days survival among 70 rats classified into vehicle (group I, n= 10; solid line), isoproterenol (group II, n = 15; thick dotted intermediate curve), isoproterenol/ sildenafil (group III, n = 15; thick dashed curve), sildenafil/vehicle(group IV, n = 15; solid line) and sildenafil/isoproternol/ Nω-nitro-L-arginine (group V, n = 15; thin dash-dot line to the left). Significant improvement in survival rate was found by log-rank test in group III compared to groups II and V (P < 0.05).

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BMC Pharmacology

ISSN: 1471-2210