Hypoglycemic and anti-lipemic effects of the aqueous extract from Cissus sicyoides

BMC Pharmacology

Table 2 Effects of the aqueous extract from Cissus sicyoides (AECS) on blood total cholesterol and triglyceride levels in alloxan-induced diabetic rats

Group	Cholesterol (mg/dL) Before	Cholesterol (mg/dL) After	Triglycerides (mg/dL) Before	Triglycerides (mg/dL) After
Control (7)	87.0 ± 5.15	74.0 ± 2.93	244.0 ± 29.65	286.8 ± 58.23
AECS
100 mg/kg, p.o. (20)	76. 8 ± 3.94	78.1 ± 5.18	222.1 ± 26.40	111.5 ± 9.51*
200 mg/kg, p.o. (13)	86.4 ± 2.96	73.2 ± 3.27	294.0 ± 32.89	171.1 ± 19.13*

Values are means ± SEM of the number of animals (in parenthesis). The blood was collected from the orbital sinus, 48 h after alloxan administration, 60 mg/kg, i.v., before and 1 h after the last administration of distilled water (control group) or AECS, administered daily for 7 days. *p < 0.05 as compared to the same group, 48 h after alloxan injection (ANOVA and Tukey as the post hoc test).