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Table 3 Ten Predicted potent peptide inhibitors of caspase-3

From: A novel method for evaluation and screening of caspase inhibitory peptides by the amino acid positional fitness score

 

Peptide

ΔGbind (kcal/mol)

APF score

1

DEVD

-16.15

0.73

2

QEPD

-15.91

0.60

3

TEPD

-15.75

0.53

4

DELD

-15.65

0.59

5

QELD

-15.63

0.56

6

LEPD

-15.57

0.49

7

DNLD

-15.45

0.52

8

DQPD

-15.39

0.54

9

DPFD

-15.16

0.51

10

NEPD

-14.95

0.50