Figure 6

The locations of peptides (from Table 1) and sequences of cleavage sites in the sorted comprehensive peptide libraries (a) caspase-3, (b) caspase-7, (c) caspase-8, and (d) caspase-9. Hatched squares show the Enriched libraries. Columns of inhibitors show ranking, sequence, APF score and Ki, column of cleavage sites shows ranking, sequence, APF score and substrate proteins, and column of optimal sequence shows ranking, sequence, and APF score. These cleavage sites of caspase-3 have been published elsewhere [17,25,29-36]. The optimal recognition sequences are identified from PS-SCL [14].