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Figure 2 | BMC Pharmacology

Figure 2

From: Mutational analysis of molecular requirements for the actions of general anaesthetics at the γ-aminobutyric acidA receptor subtype, α1β2γ2

Figure 2

Modulatory action of intravenous general anesthetic at α1β2γ2 GABAA receptors. (a) Single traces of the effects of the intravenous anaesthetics propofol (Prop), etomidate (Etom) and alphaxalone (Alphax) on GABA-evoked chloride currents. (b) The potentiation of the GABA-evoked chloride currents is expressed relative to the control currents at the given GABA concentration (means ± standard error, n = 10–17; *p < 0.05; Student's t-test).

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BMC Pharmacology

ISSN: 1471-2210