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Figure 5 | BMC Pharmacology

Figure 5

From: The orthosteric agonist 2-chloro-5-hydroxyphenylglycine activates mGluR5 and mGluR1 with similar efficacy and potency

Figure 5

Effect of selective inhibitors on CHPG effects in mGluR5b and 1a expressing cells. Average (± SEM) calcium current inhibition produced by application of 1 mM CHPG alone (black) or in the presence of 1 μM MPEP (gray) or 50 μM LY367385 (white) in SCG neurons expressing the indicated receptor. Number of cells in each group shown in parentheses.

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BMC Pharmacology

ISSN: 1471-2210