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Figure 4 | BMC Pharmacology

Figure 4

From: Polyamidoamine (PAMAM) dendrimer conjugate specifically activates the A3 adenosine receptor to improve post-ischemic/reperfusion function in isolated mouse hearts

Figure 4

PAMAM control dendrimer, MRS5401, alone did not influence functional recovery of isolated mouse hearts subjected to 20 min ischemia/45 min reperfusion up to a concentration of 100 nM. The graph shows recovery of LVDP during reperfusion as a percent of paced baseline. The inset shows the percent recovery of the hearts at 45 min reperfusion for the rates of relaxation, contraction and coronary flow. There were no differences compared to control hearts not exposed to MRS5401.

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BMC Pharmacology

ISSN: 1471-2210