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Figure 3 | BMC Pharmacology

Figure 3

From: Polyamidoamine (PAMAM) dendrimer conjugate specifically activates the A3 adenosine receptor to improve post-ischemic/reperfusion function in isolated mouse hearts

Figure 3

cAMP functional assays. Increasing concentrations of MRS5246 or MRS5322 were added to activate mA1 or mA3ARs to inhibit forskolin-stimulated cAMP production. A & B, both compounds are much more potent at the mA3AR than at the mA1AR. C, curves from mA3ARs to compare and show MRS5246 was much more potent than MRS5233 at the mA3AR.

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BMC Pharmacology

ISSN: 1471-2210