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Figure 8 | BMC Pharmacology

Figure 8

From: Quantitative in vitro and in vivo pharmacological profile of CE-178253, a potent and selective cannabinoid type 1 (CB1) Receptor Antagonist

Figure 8

Effect of CE-178253 on FI (8A) and BW (8B) in DIO mice. FI and BW were measured in DIO mice (baseline body weight = 38.8 ± 0.7 g (Veh.), 38.7 ± 0.6 (1 mg/kg CE-178253) 38.8 ± 0.6 (3 mg/kg CE-178253); mean ± SEM, n = 10/group) daily after once daily administration of veh. (0.5% MC) or CE-178253 at either 1 mg/kg or 3 mg/kg p.o. FI data shown are the total amount of food consumed expressed in grams consumed for each day of treatment. The mean ± SEM (n = 10/group) is shown. * = p < 0.05 vs. veh.

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BMC Pharmacology

ISSN: 1471-2210