Figure 5From: Quantitative in vitro and in vivo pharmacological profile of CE-178253, a potent and selective cannabinoid type 1 (CB1) Receptor AntagonistStimulation of acute energy expenditure by CE-178253. Male S-D rats were given veh. (0.5% MC), 1 mg/kg or 3 mg/kg CE-178253 (p.o.). Energy expenditure, measured by indirect calorimetry, was measure for 2 hr before dosing and 4 hr after dosing. The mean ± SEM (n = 8/group) is displayed. * = p < 0.05 vs. veh.Back to article page