Table 3 Descriptive analysis of the kinetics of serum Neopterina and serum β2-microglobulin increments.
Variable | Formulation A N = 15 | Formulation B N = 15 | p | 90% CI |
|---|---|---|---|---|
Neopterin | ||||
AUEC (ng.h/mL) | 500 ± 332 | 474 ± 257 | 0.75 | (0.71 - 1.26) |
Rmax (ng/mL) | 3.6 ± 1.9 | 3.8 ± 2.1 | 0.79 | (0.75 - 1.48) |
T(Rmax) (h) | 48 ± 24 | 48 ± 24 | 0.19 | (0.61 - 1.00) |
MET (h) | 104 ± 36.5 | 108 ± 34.2 | 0.66 | (0.88 - 1.24) |
RAV | 0.010 ± 0.007 | 0.009 ± 0.003 | 0.865 | (0.76 - 1.20) |
β2-microglobulin | ||||
AUEC (μg.h/mL) | 211 ± 145 | 190 ± 95 | 0.50 | (0.70 - 1.16) |
Rmax (μg/mL) | 1.2 ± 0.5 | 1.2 ± 0.5 | 0.99 | (0.83 - 1.22) |
T(Rmax) (h) | 72 ± 72 | 72 ± 24 | 0.10 | (0.58 - 1.00) |
MET (h) | 131 ± 43 | 161 ± 63 | 0.09 | (1.01 - 1.50) |
RAV | 0.008 ± 0.005 | 0.006 ± 0.001 | 0.37 | (0.71 - 1.11) |