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Table 2 Significant values of the correlation between biomarkers and liver and renal histopathological changes based on Spearman rank correlation test.

From: Histopathology and biochemistry analysis of the interaction between sunitinib and paracetamol in mice

Biomarker

Liver changes

Kidney changes

 

Vascular

Inflammatory

Vascular

Inflammatory

AST

p < 0.01

p < 0.01

n/a

n/a

ALT

p < 0.01

p < 0.01

n/a

n/a

BUN

n/a

n/a

p < 0.01

p < 0.01

Creatinine

n/a

n/a

p > 0.05

p > 0.05

  1. The correlation is significant if p < 0.01.
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BMC Pharmacology

ISSN: 1471-2210