Table 1 Pharmacokinetics of artesunate and dihydroartemisinin in rats having received a single dose of artesunate
From: Pharmacokinetics of artesunate after single oral administration to rats
Drug | Cmax (ng/ml) | Tmax (min) | AUC0-t (ngmin/ml) | T1/2 absorption (min) |
|---|---|---|---|---|
Artesunate | 713.1 ± 233.3 | 5.0 ± 0.0 | 18968 ± 8012.4 | 2.73 +/- 0.85 |
Dihydroartemisinin | 2040.3 ± 650.0 | 37.5 ± 8.7 | 74500 ± 16806.1 | 12.49 +/- 2.49 |