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Regulation of soluble guanylyl cyclase by phosphorylation

Authors: Zongmin Zhou, Nazish Sayed, Anastasia Pyriochou, David Fulton, Annie Beuve and Andreas Papapetropoulos

Citation: BMC Pharmacology 2009 9(Suppl 1):P80

Content type: Poster presentation Published on: 11 August 2009

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Effect of exercise training on endothelium-dependent relaxing response and cGMP concentration in pulmonary artery from rats submitted to lung ischemia/reperfusion

Authors: Angelina Zanesco, Maria A Delbin, Ana PC Davel, Fernando R Bau, Fernanda BM Priviero, Luciana V Rossoni and Edson Antunes

Citation: BMC Pharmacology 2009 9(Suppl 1):P77

Content type: Poster presentation Published on: 11 August 2009

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Possible identification of novel natriuretic peptide receptor phosphorylation sites by alanine/glutamate mutagenesis

Authors: Andrea R Yoder, Kathryn A Barbieri, Jerid W Robinson and Lincoln R Potter

Citation: BMC Pharmacology 2009 9(Suppl 1):P76

Content type: Poster presentation Published on: 11 August 2009

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Therapeutic potential of CNP for skeletal dysplasias

Authors: Akihiro Yasoda, Hidetomo Kitamura, Toshihito Fujii, Eri Kondo, Naoaki Murao, Masako Miura, Naotetsu Kanamoto, Yasato Komatsu, Hiroshi Arai and Kazuwa Nakao

Citation: BMC Pharmacology 2009 9(Suppl 1):P74

Content type: Poster presentation Published on: 11 August 2009

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Role of the general base Glu268 in nitroglycerin bioactivation and mechanism-based superoxide formation by aldehyde dehydrogenase-2

Authors: M Verena Wenzl, Matteo Beretta, Antonius CF Gorren, Pravas K Baral, Karl Gruber, Michael Russwurm, Doris Koesling, Kurt Schmidt and Bernd Mayer

Citation: BMC Pharmacology 2009 9(Suppl 1):P72

Content type: Poster presentation Published on: 11 August 2009

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Is kynurenine a novel and important vasodilator in human septic shock?

Authors: Yutang Wang, Dechaboon Changsiri, Gavin McKenzie, Johannes-Peter Stasch, Michael Hahn, C Woolfe, D Rajbhandari, David S Celermajer and Roland Stocker

Citation: BMC Pharmacology 2009 9(Suppl 1):P70

Content type: Poster presentation Published on: 11 August 2009

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Blockade of CNG channels abrogates urethral relaxation induced by soluble guanylate cyclase activation

Authors: Domingo Triguero, Maria Sancho, Marta García-Flores and Ángeles García-Pascual

Citation: BMC Pharmacology 2009 9(Suppl 1):P69

Content type: Poster presentation Published on: 11 August 2009

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Mechanisms of relaxant activity of BAY 41-2272 in rat tracheal smooth muscle in vitro

Authors: Haroldo AF Toque, Rafael P Morganti, Gilberto De Nucci and Edson Antunes

Citation: BMC Pharmacology 2009 9(Suppl 1):P68

Content type: Poster presentation Published on: 11 August 2009

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Sensitive assay for the detection of cyclic nucleotides by mass spectrometry

Authors: Corinna M Spangler, Bettina Wilhelm, Heike Burhenne, Kerstin Rauch, Roland Seifert and Volkhard Kaever

Citation: BMC Pharmacology 2009 9(Suppl 1):P66

Content type: Poster presentation Published on: 11 August 2009

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NO/cGMP signalling in platelets

Authors: Elisabeth Schinner and Jens Schlossmann

Citation: BMC Pharmacology 2009 9(Suppl 1):P62

Content type: Poster presentation Published on: 11 August 2009

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NO inhibits platelet apoptosis by cGMP-dependent and-independent pathways

Authors: Natalia Rukoyatkina, Ulrich Walter and Stepan Gambaryan

Citation: BMC Pharmacology 2009 9(Suppl 1):P60

Content type: Poster presentation Published on: 11 August 2009

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Pharmacological preconditioning with the guanylate cyclase activator cinaciguat (BAY 58-2667) protects against reperfusion injury after cardiopulmonary bypass

Authors: Tamás Radovits, Sevil Korkmaz, Sivakkanan Loganathan, Johannes-Peter Stasch, Matthias Karck and Gábor Szabó

Citation: BMC Pharmacology 2009 9(Suppl 1):P56

Content type: Poster presentation Published on: 11 August 2009

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Effect of L-carnitine supplementation on the sGC/cGMP pathway in vascular relaxing responses from exercised rats

Authors: Fernanda BM Priviero, Julio A Rojas-Moscoso, Alexandre S Silva, Edson Antunes and Angelina Zanesco

Citation: BMC Pharmacology 2009 9(Suppl 1):P54

Content type: Poster presentation Published on: 11 August 2009

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Acute hemodynamic response to single oral doses of BAY 60-4552, a soluble guanylate cyclase stimulator, in patients with biventricular heart failure

Authors: Veselin Mitrovic, B Swidnicki, Ardeschir Ghofrani, Wolfgang Mück, Nina Kirschbaum, Joachim Mittendorf, Johannes-Peter Stasch, Georg Wensing, Reiner Frey and Silvia Lentini

Citation: BMC Pharmacology 2009 9(Suppl 1):P51

Content type: Poster presentation Published on: 11 August 2009

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Receptor guanylyl cyclases in mammalian olfaction: from genes to function

Authors: Frank Zufall

Citation: BMC Pharmacology 2009 9(Suppl 1):S45

Content type: Oral presentation Published on: 11 August 2009

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Cross-talk of inhibitory and stimulatory signalling pathways of human platelets

Authors: Ulrich Walter and Stepan Gambaryan

Citation: BMC Pharmacology 2009 9(Suppl 1):S43

Content type: Oral presentation Published on: 11 August 2009

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Phosphodiesterase-5 inhibition delays cardiac dilation and improves myocardial function in a rat model of heart failure due to chronic volume overload

Authors: Sivakkanan Loganathan, Tamás Radovits, Kristóf Hirschberg, Sevil Korkmaz, Matthias Karck and Gábor Szabó

Citation: BMC Pharmacology 2009 9(Suppl 1):P41

Content type: Poster presentation Published on: 11 August 2009

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Cyclic GMP signalling in human ES and iPS-derived vascular cells

Authors: Daisuke Taura, Masakatsu Sone, Koichiro Homma, Kenichi Yamahara and Kazuwa Nakao

Citation: BMC Pharmacology 2009 9(Suppl 1):S40

Content type: Oral presentation Published on: 11 August 2009

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Kynurenine is a novel endothelium-derived vascular relaxing factor produced during inflammation

Authors: Yutang Wang, Hanzhong Liu, Gavin McKenzie, Paul K Witting, Johannes-Peter Stasch, Michael Hahn, Katherine A Jackman, Dechaboon Changsirivathanathamrong, Ben J Wu, Helen J Ball, Shane R Thomas, David S Celermajer, Andrew L Mellor, Chris G Sobey, John F Keaney Jr, Nicholas H Hunt…

Citation: BMC Pharmacology 2009 9(Suppl 1):S39

Content type: Oral presentation Published on: 11 August 2009

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Protein kinase G modulates human myocardial passive stiffness by phosphorylation of the titin springs

Authors: Martina Krüger, Sebastian Kötter, Anika Grützner, Patrick Lang, Christian Andresen, argaret M Redfield, Elke Butt, Cris G dos Remedios and Wolfgang A Linke

Citation: BMC Pharmacology 2009 9(Suppl 1):P37

Content type: Poster presentation Published on: 11 August 2009

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Pharmacological activation of soluble guanylate cyclase activator protects the heart against isoproterenol-induced myocardial ischemia in rats

Authors: Sevil Korkmaz, Tamás Radovits, Enikő Barnucz, Kristóf Hirschberg, Philipp Neugebauer, Sivakkanan Loganathan, Stefan Zöllner, Szabolcs Páli, Beatrice Seidel, Matthias Karck and Gábor Szabó

Citation: BMC Pharmacology 2009 9(Suppl 1):P35

Content type: Poster presentation Published on: 11 August 2009

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The PKG1 specific phosphorylation substrate cysteine-rich protein 2 knockout decreases blood pressure and intimal hyperplasia

Authors: Matthias Sausbier, Usamah Abdullah, Ulrike Sausbier, Yi-Liu Liao, Hong Zhao, Marcus Makowski, Susanne Feil, Robert Feil, Franz Hofmann, Alfred Nordheim, René Botnar and Peter Ruth

Citation: BMC Pharmacology 2009 9(Suppl 1):S33

Content type: Oral presentation Published on: 11 August 2009

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C-type natriuretic peptide is a Schwann cell-derived factor for development and function of sensory neurons

Authors: Ichiro Kishimoto, Takeshi Tokudome, Hideki Chusho, Kazuwa Nakao and Kenji Kangawa

Citation: BMC Pharmacology 2009 9(Suppl 1):P33

Content type: Poster presentation Published on: 11 August 2009

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Janus-faced signaling of cGMP in acute lung injury

Authors: R Scott Stephens, O Rentsendorj, Eric P Schmidt, Paul Hassoun, Aigul Moldobaeva and David B Pearse

Citation: BMC Pharmacology 2009 9(Suppl 1):S31

Content type: Oral presentation Published on: 11 August 2009

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Nitroxyl, the novel redox sibling of NO, suppresses cerebrovascular NADPH oxidase

Authors: Barbara Kemp-Harper, Ravina Ravi, Michelle Bullen, Rebecca Ritchie, Christopher Sobey and Alyson Miller

Citation: BMC Pharmacology 2009 9(Suppl 1):P31

Content type: Poster presentation Published on: 11 August 2009

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Cardioprotective effects in aged spontaneously hypertensive rats due to chronic stimulation/activation of sGC without hypotension

Authors: Emma S Jones, Barbara K Kemp-Harper, Johannes-Peter Stasch, Harald HHW Schmidt and Robert E Widdop

Citation: BMC Pharmacology 2009 9(Suppl 1):P29

Content type: Poster presentation Published on: 11 August 2009

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A novel designer natriuretic peptide CD-NP suppresses TGF-beta 1 induced collagen Type I production in human cardiac fibroblasts

Authors: Tomoko Ichiki, Brenda K Huntley, S Jeson Sangaralingham, Horng H Chen and John C Burnett Jr

Citation: BMC Pharmacology 2009 9(Suppl 1):P27

Content type: Poster presentation Published on: 11 August 2009

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Subcellular distribution of cGMP signalling proteins in VSMCs of IRAG KO mice

Authors: Bernhard Hieke and Jens Schlossmann

Citation: BMC Pharmacology 2009 9(Suppl 1):P25

Content type: Poster presentation Published on: 11 August 2009

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Phosphodiesterase-5 inhibition and cardioprotection: potential role of hydrogen sulfide

Authors: Rakesh C Kukreja, Vinh Q Chau, Nicholas N Hoke, Antonio Abbate, Amit Varma, Ramzi A Ockaili, Stefano Toldo and Fadi N Salloum

Citation: BMC Pharmacology 2009 9(Suppl 1):S24

Content type: Oral presentation Published on: 11 August 2009

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The natriuretic peptide/guanylyl cyclase-A system functions as a stress-responsive regulator of angiogenesis in mice

Authors: Michaela Kuhn, Kristine Schwarz, Michael Hartmann, Javier Carbajo-Lozoya, Ulrich Flögel, Jörg Stypmann, Martin van Eickels, Stepan Gambaryan, Thomas Wieland and Hideo A Baba

Citation: BMC Pharmacology 2009 9(Suppl 1):S23

Content type: Oral presentation Published on: 11 August 2009

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Crosstalk of cyclic GMP dependent kinase I and BMP signaling

Authors: Eva Heining, Raphaela Schwappacher, D Horbelt, Otmar Huber and Petra Knaus

Citation: BMC Pharmacology 2009 9(Suppl 1):P23

Content type: Poster presentation Published on: 11 August 2009

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A splice variant of the guanylyl cyclase-A receptor interferes with atrial natriuretic peptide (ANP) signaling

Authors: Michael Hartmann, Katharina Völker, Birgit Gaßner, Juliane Schröter, Beatrice Dankworth, Thomas Müller, Viacheslav O Nikolaev and Michaela Kuhn

Citation: BMC Pharmacology 2009 9(Suppl 1):P22

Content type: Poster presentation Published on: 11 August 2009

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Yin and Yang of cGMP signalling in hydrostatic lung edema

Authors: Jun Yin, Stephanie M Kaestle, Michael Mertens and Wolfgang M Kuebler

Citation: BMC Pharmacology 2009 9(Suppl 1):S22

Content type: Oral presentation Published on: 11 August 2009

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Direct evidence for close proximity of catalytic and regulatory domains of heterodimeric sGC based on fluorescence resonance energy transfer

Authors: Tobias Haase, Nadine Haase and Soenke Behrends

Citation: BMC Pharmacology 2009 9(Suppl 1):P21

Content type: Poster presentation Published on: 11 August 2009

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Cyclic GMP-dependent protein kinase II promotes chondrocyte hypertrophy and skeletal growth

Authors: Hiroshi Kawaguchi, Hirotaka Chikuda, Yosuke Kawasaki and Franz Hofmann

Citation: BMC Pharmacology 2009 9(Suppl 1):S20

Content type: Oral presentation Published on: 11 August 2009

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Blood pressure-independent effects of enhanced NO/cGMP signalling and gender on aortic remodelling in experimental renal hypertension

Authors: Bianca Grosz, Stephanie Krämer, Tanja Loof, Hans H Neumayer, Yingrui Wang-Rosenke and Harm Peters

Citation: BMC Pharmacology 2009 9(Suppl 1):P19

Content type: Poster presentation Published on: 11 August 2009

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Novel mechanisms of anti-hypertrophic effects from PDE5A inhibition

Authors: David A Kass, Norimichi Nagayama, Manling Zhang, Dong-ik Lee, Steven Hsu, Elizabeth Ketner and Eiki Takimoto

Citation: BMC Pharmacology 2009 9(Suppl 1):S18

Content type: Oral presentation Published on: 11 August 2009

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Bioactivation of pentaerythrityl tetranitrate by mitochondrial aldehyde dehydrogenase

Authors: Martina Griesberger, Gerald Wölkart, Antonius Gorren, Matteo Beretta, Verena Wenzl, Juliane Brettschneider, Andreas Seeling, Jochen Lehmann, Michael Russwurm, Doris Koesling, Kurt Schmidt and Bernd Mayer

Citation: BMC Pharmacology 2009 9(Suppl 1):P17

Content type: Poster presentation Published on: 11 August 2009

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Warfarin pharmacodynamics and pharmacokinetics are not affected by the soluble guanylate cyclase stimulator riociguat (BAY 63-2521)

Authors: Reiner Frey, Wolfgang Mück, Nina Kirschbaum, Jörn Krätzschmar, Gerrit Weimann and Georg Wensing

Citation: BMC Pharmacology 2009 9(Suppl 1):P15

Content type: Poster presentation Published on: 11 August 2009

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Riociguat dose titration in patients with chronic thromboembolic pulmonary hypertension (CTEPH) or pulmonary arterial hypertension (PAH)

Authors: Hossein A Ghofrani, Marius M Hoeper, Gert Hoeffken, Michael Halank, Gerrit Weimann and Friedrich Grimminger

Citation: BMC Pharmacology 2009 9(Suppl 1):S14

Content type: Oral presentation Published on: 11 August 2009

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NO signalling in mice lacking the NO receptor guanylyl cyclase

Authors: Dieter Groneberg, Peter König, Doris Koesling and Andreas Friebe

Citation: BMC Pharmacology 2009 9(Suppl 1):S12

Content type: Oral presentation Published on: 11 August 2009

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Molecular mechanisms underlying pharmacological stimulation of eNOS expression and eNOS activity

Authors: Huige Li, Ning Xia, Andreas Daiber, Alice Habermeier, Qing Lu, Matthias Oelze, Ellen I Closs, Thomas Münzel and Ulrich Förstermann

Citation: BMC Pharmacology 2009 9(Suppl 1):S11

Content type: Oral presentation Published on: 11 August 2009

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Redox regulation of protein kinase G

Authors: Philip Eaton

Citation: BMC Pharmacology 2009 9(Suppl 1):S10

Content type: Oral presentation Published on: 11 August 2009

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Modulating cGMP in heart failure by novel natriuretic peptides

Authors: John C Burnett Jr

Citation: BMC Pharmacology 2009 9(Suppl 1):S8

Content type: Oral presentation Published on: 11 August 2009

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Renal targeted protein therapeutics in experimental overt heart failure with renal dysfunction

Authors: Horng H Chen, Alessandro Cataliotti, Fernando L Martin, John A Schirger and John C Burnett Jr

Citation: BMC Pharmacology 2009 9(Suppl 1):P7

Content type: Poster presentation Published on: 11 August 2009

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Phenotypes of sGC mutant mice in basic conditions, disease and shock

Authors: Peter Brouckaert, Anje Cauwels, Robrecht Thoonen, Emmanuel Buys, KD Bloch, Patrick Sips, Fumito Ichinose, Elke Rogge, Sofie Nimmegeers, Johan Van de Voorde, Romain Lefebvre and Johannes-Peter Stasch

Citation: BMC Pharmacology 2009 9(Suppl 1):S6

Content type: Oral presentation Published on: 11 August 2009

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sGCα₁β₁ attenuates cardiac dysfunction and mortality in murine inflammatory shock models

Authors: Emmanuel S Buys, Anje Cauwels, Michael J Raher, Jonathan J Passeri, Ion Hobai, Sharon M Cawley, Kristen M Rauwerdink, Helene Thibault, Patrick Y Sips, Robrecht Thoonen, Marielle Scherrer-Crosbie, Fumito Ichinose, Peter Brouckaert and Kenneth D Bloch

Citation: BMC Pharmacology 2009 9(Suppl 1):P5

Content type: Poster presentation Published on: 11 August 2009

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B-type natriuretic peptide single nucleotide polymorphism rs198389 and survival in the general community

Authors: Guido Boerrigter, Lisa C Costello-Boerrigter, Syed Ameenuddin, Douglas W Mahoney, Joshua P Slusser, Denise M Heublein, Margaret M Redfield, Richard J Rodeheffer, Timothy M Olson and John C Burnett

Citation: BMC Pharmacology 2009 9(Suppl 1):P4

Content type: Poster presentation Published on: 11 August 2009

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Thiol-dependent redox modulation of soluble guanylyl cyclase

Authors: Padma Baskaran, Samba Couloubaly, Jamila Hedhli, Chirag Patel, Smita Shukla and Annie Beuve

Citation: BMC Pharmacology 2009 9(Suppl 1):S4

Content type: Oral presentation Published on: 11 August 2009

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Bioactivation of nitroglycerin by the East Asian variant of aldehyde dehydrogenase-2

Authors: Matteo Beretta, Antonius CF Gorren, M Verena Wenzl, Robert Weis, Michael Russwurm, Doris Koesling, Kurt Schmidt and Bernd Mayer

Citation: BMC Pharmacology 2009 9(Suppl 1):P3

Content type: Poster presentation Published on: 11 August 2009

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