Articles
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Citation: BMC Pharmacology 2010 10(Suppl 1):A48
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Dose-response assessment of tariquidar for inhibition of P-glycoprotein at the human blood-brain barrier using (R)-[11C]verapamil PET
Citation: BMC Pharmacology 2010 10(Suppl 1):A47 -
Small-animal PET evaluation of [11C]MC113 as a PET tracer for P-glycoprotein
Citation: BMC Pharmacology 2010 10(Suppl 1):A46 -
Tissue pharmacokinetics of individual macrolides support observed differences in development of bacterial resistance
Citation: BMC Pharmacology 2010 10(Suppl 1):A45 -
Inhibition of tissue factor pathway inhibitor (TFPI) by ARC19499 improves clotting of hemophiliac blood
Citation: BMC Pharmacology 2010 10(Suppl 1):A44 -
Thrombus formation is not pH-dependent
Citation: BMC Pharmacology 2010 10(Suppl 1):A43 -
Vertical inhibition of the mTORC1/mTORC2/PI3K pathway shows synergistic effects against melanoma in vitro and in vivo
Citation: BMC Pharmacology 2010 10(Suppl 1):A42 -
BEZ235 impairs gastric cancer growth by inhibition of PI3K/mTOR in vitro and in vivo
Citation: BMC Pharmacology 2010 10(Suppl 1):A41 -
The influence of lutein supplementation on macular pigment optical density in patients with dry AMD compared with healthy control subjects
Citation: BMC Pharmacology 2010 10(Suppl 1):A40 -
Antimicrobial activity of antibiotics in urine under different physiological conditions
Citation: BMC Pharmacology 2010 10(Suppl 1):A39 -
Does VEGF polymorphism play a role in the treatment success with VEGF inhibitors in patients with CNV?
Citation: BMC Pharmacology 2010 10(Suppl 1):A38 -
Endotoxin-induced microparticle formation is subject to tolerance development in humans
Citation: BMC Pharmacology 2010 10(Suppl 1):A37 -
Teicoplanin pharmacokinetics during albumin dialysis
Citation: BMC Pharmacology 2010 10(Suppl 1):A36 -
Short-chain methotrexate polyglutamate MTXPG2 as outcome parameter in rheumatoid arthritis
Citation: BMC Pharmacology 2010 10(Suppl 1):A35 -
Fear learning triggers structural changes at GABAergic synapses in the basal amygdala
Citation: BMC Pharmacology 2010 10(Suppl 1):A34 -
Neuropeptide Y in the basolateral amygdala modulates the acquisition of conditioned fear
Citation: BMC Pharmacology 2010 10(Suppl 1):A33 -
Endogenous dynorphin in emotional control and stress response revisited
Citation: BMC Pharmacology 2010 10(Suppl 1):A32 -
Luminescence resonance energy transfer-based intramolecular distance measurements in leucine transporter from Aquifex aeolicus
Citation: BMC Pharmacology 2010 10(Suppl 1):A31 -
Tracking the A2A adenosine receptor
Citation: BMC Pharmacology 2010 10(Suppl 1):A30 -
The pulmonary microvascular endothelial barrier function is controlled by the PGE2-EP4 signaling axis
Citation: BMC Pharmacology 2010 10(Suppl 1):A29 -
Selective serotonin reuptake inhibitor-induced cell death: in search of a mechanism
Citation: BMC Pharmacology 2010 10(Suppl 1):A28 -
Conformation of membrane-inserted P-glycoprotein
Citation: BMC Pharmacology 2010 10(Suppl 1):A27 -
The interactome of the A2A adenosine receptor in vitro and in vivo
Citation: BMC Pharmacology 2010 10(Suppl 1):A26 -
The permanently charged lidocaine analogue QX222 acts as a blocker from the intracellular side and as an inactivation modulator from the extracellular side in a mutant NaV1.4 channel
Citation: BMC Pharmacology 2010 10(Suppl 1):A24 -
4-Methylthioamphetamine (4-MTA) induces mitochondrial-dependent apoptosis in SH-SY5Y cells independently of dopamine and noradrenaline transporters
Citation: BMC Pharmacology 2010 10(Suppl 1):A22 -
The high-affinity binding site for tricyclic antidepressants resides in the outer vestibule of the serotonin transporter
Citation: BMC Pharmacology 2010 10(Suppl 1):A21 -
α-N-Heterocyclic thiosemicarbazones induce ER stress-mediated CHOP activation
Citation: BMC Pharmacology 2010 10(Suppl 1):A20 -
The role of the carboxyl terminus in folding of the serotonin transporter
Citation: BMC Pharmacology 2010 10(Suppl 1):A18 -
A biological target for antiplatelet therapy: the prostaglandin E2 receptor EP4
Citation: BMC Pharmacology 2010 10(Suppl 1):A17 -
Interaction of manganese with striatal dopamine turnover in human alpha-synuclein transgenic mice
Citation: BMC Pharmacology 2010 10(Suppl 1):A16 -
Molecular engineering of the TRPC3 pore structure identifies Ca2+ permeation through TRPC3 channels as a key determinant of cardiac calcineurin/NFAT signaling
Citation: BMC Pharmacology 2010 10(Suppl 1):A15 -
Effects on cell proliferation and EPR spin trapping studies of Abnormal Savda Munziq and its chromatographic subfractions
Citation: BMC Pharmacology 2010 10(Suppl 1):A14 -
Interactions of peripheral and central μ opioid systems during emotional stress
Citation: BMC Pharmacology 2010 10(Suppl 1):A13 -
Long-term regulation of ATP-binding cassette transporters on mRNA and protein level by simvastatin in human rhabdomyosarcoma and neuroblastoma cells
Citation: BMC Pharmacology 2010 10(Suppl 1):A12 -
Concentrative ER export of the serotonin transporter relies exclusively on an interaction with Sec24C
Citation: BMC Pharmacology 2010 10(Suppl 1):A11 -
Toxicity of ascaridole from Chenopodium ambrosioides in mammalian mitochondria
Citation: BMC Pharmacology 2010 10(Suppl 1):A10 -
Is thymoquinone an antioxidant?
Citation: BMC Pharmacology 2010 10(Suppl 1):A9 -
Signalling and function of the human G protein-coupled receptor 55
Citation: BMC Pharmacology 2010 10(Suppl 1):A8 -
Cross-talk of PGD2 receptors: the DP receptor modulates signaling and trafficking of CRTH2
Citation: BMC Pharmacology 2010 10(Suppl 1):A7 -
The interplay of excitatory and inhibitory coupling modes is crucial for the regulation of neuronal electrical activities by L-type calcium channels
Citation: BMC Pharmacology 2010 10(Suppl 1):A6 -
Enhanced fear expression in a psychphathological mouse model of trait anxiety: pharmacological interventions
Citation: BMC Pharmacology 2010 10(Suppl 1):A5 -
A ligand-based 3D pharmacophore model for the μ opioid receptor: application to the morphinan class of opioids
Citation: BMC Pharmacology 2010 10(Suppl 1):A4 -
Resveratrol reduces myofibroblast arrhythmogenicity
Citation: BMC Pharmacology 2010 10(Suppl 1):A3 -
Effect of rat common carotid artery occlusion on vascular action of adenosine
Citation: BMC Pharmacology 2010 10(Suppl 1):A2 -
Histopathology and biochemistry analysis of the interaction between sunitinib and paracetamol in mice
Sunitinib, a tyrosine kinase inhibitor to treat GIST and mRCC may interact with paracetamol as both undergo P450 mediated biotransformation and P-glycoprotein transport. This study evaluates the effects of sun...
Citation: BMC Pharmacology 2010 10:14 -
Protective efficacy of natansnin, a dibenzoyl glycoside from Salvinia natans against CCl4 induced oxidative stress and cellular degeneration in rat liver
Carbon tetra chloride (CCl4), an industrial solvent, is a hepatotoxic agent and it is the well established animal model for free radical-induced liver injury. The present investigation was carried out to establis...
Citation: BMC Pharmacology 2010 10:13 -
Hematopoietic stem cells exhibit a specific ABC transporter gene expression profile clearly distinct from other stem cells
ATP-binding cassette (ABC) transporters protect cells against unrelated (toxic) substances by pumping them across cell membranes. Earlier we showed that many ABC transporters are highly expressed in hematopoie...
Citation: BMC Pharmacology 2010 10:12 -
Beneficial effect of agmatine on brain apoptosis, astrogliosis, and edema after rat transient cerebral ischemia
Although agmatine therapy in a mouse model of transient focal cerebral ischemia is highly protective against neurological injury, the mechanisms underlying the protective effects of agmatine are not fully eluc...
Citation: BMC Pharmacology 2010 10:11 -
Salvianolic acid B functioned as a competitive inhibitor of matrix metalloproteinase-9 and efficiently prevented cardiac remodeling
Infarct-induced left ventricular (LV) remodeling is a deleterious consequence after acute myocardial infarction (MI) which may further advance to congestive heart failure. Therefore, new therapeutic strategies...
Citation: BMC Pharmacology 2010 10:10 -
Quantitative in vitro and in vivo pharmacological profile of CE-178253, a potent and selective cannabinoid type 1 (CB1) Receptor Antagonist
Cannabinoid 1 (CB1) receptor antagonists exhibit pharmacological properties favorable for the treatment of obesity and other related metabolic disorders. CE-178253 (1-[7-(2-Chlorophenyl)-8-(4-chlorophenyl)-2-meth...
Citation: BMC Pharmacology 2010 10:9