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  1. Authors: Soni Pullamsetti, Ladislau Kiss, Hossein Ardeschir Ghofrani, Robert Voswinckel, Peter Haredza, Walter Klepetko, Clemens Aigner, Ludger Fink, Jai Prakash Muyal, Norbert Weissmann, Friedrich Grimminger, Werner Seeger and Ralph Theo Schermuly

    Citation: BMC Pharmacology 2005 5(Suppl 1):P45

    Content type: Poster presentation

    Published on:

    This article is part of a Supplement: Volume 5 Supplement 1

  2. Authors: Rio Dumitrascu, Norbert Weissmann, Hossein Ardeschir Ghofrani, Knut Beuerlein, Harald Schmidt, Johannes-Peter Stasch, Markus Gnoth, Werner Seeger, Friedrich Grimminger and Ralph Theo Schermuly

    Citation: BMC Pharmacology 2005 5(Suppl 1):P16

    Content type: Poster presentation

    Published on:

    This article is part of a Supplement: Volume 5 Supplement 1

  3. Cardiac hypertrophy is a major risk factor for morbidity and mortality in a number of cardiovascular diseases. Consequently, the signaling pathways that inhibit cardiac hypertrophy are currently receiving much...

    Authors: Madiha AH Hassan and Amal F Ketat

    Citation: BMC Pharmacology 2005 5:10

    Content type: Research article

    Published on:

  4. Thromboxane B2 (TXB2) and superoxide anion (O2-) are neuroinflammatory mediators that appear to be involved in the pathogenesis of several neurodegenerative diseases. Because activated-microglia are the main sour...

    Authors: Alejandro MS Mayer, Mary L Hall, Sean M Lynch, Sarath P Gunasekera, Susan H Sennett and Shirley A Pomponi

    Citation: BMC Pharmacology 2005 5:6

    Content type: Research article

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  5. There have been few reports of pharmacokinetic models that have been linked to models of the cardiovascular system. Such models could predict the cardiovascular effects of a drug under a variety of circumstanc...

    Authors: Richard N Upton and Guy L Ludbrook

    Citation: BMC Pharmacology 2005 5:5

    Content type: Research article

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  6. The nucleoside analog cladribine is used for the treatment of a variety of indolent B- and T-cell lymphoid malignancies. The primary aim of the study was to evaluate the population distribution of pharmacokine...

    Authors: Synnöve Lindemalm, Radojka M Savic, Mats O Karlsson, Gunnar Juliusson, Jan Liliemark and Freidoun Albertioni

    Citation: BMC Pharmacology 2005 5:4

    Content type: Research article

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  7. Ethanol inhibits proliferation in astrocytes, an effect that was recently linked to the suppression of phosphatidic acid (PA) formation by phospholipase D (PLD). The present study investigates ethanol's effect...

    Authors: Beate Schatter, Shenchu Jin, Konrad Löffelholz and Jochen Klein

    Citation: BMC Pharmacology 2005 5:3

    Content type: Research article

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  8. CCl4 is a well-established hepatotoxin inducing liver injury by producing free radicals. Exposure to CCl4 also induces acute and chronic renal injuries. The present study was designed to establish the protective ...

    Authors: Naveen Tirkey, Sangeeta Pilkhwal, Anurag Kuhad and Kanwaljit Chopra

    Citation: BMC Pharmacology 2005 5:2

    Content type: Research article

    Published on:

  9. Before therapeutic effect is obtained after treatment with antidepressant drugs, like serotonin selective reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs) and monoamine oxidase inhibitors (MAO-Is)...

    Authors: Cecilia Berggard, Mattias Damberg and Lars Oreland

    Citation: BMC Pharmacology 2005 5:1

    Content type: Research article

    Published on:

  10. Bisdioxopiperazine anti-cancer agents are inhibitors of eukaryotic DNA topoisomerase II, sequestering this protein as a non-covalent protein clamp on DNA. It has been suggested that such complexes on DNA repre...

    Authors: Lars H Jensen, Marielle Dejligbjerg, Lasse T Hansen, Morten Grauslund, Peter B Jensen and Maxwell Sehested

    Citation: BMC Pharmacology 2004 4:31

    Content type: Research article

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  11. Reserpine, an alkaloid from Rauwolfia serpentina was widely used for its antihypertensive action in the past. In later years, its use has been reduced because of precipitation of depression and extra pyramidal sy...

    Authors: Satyanarayana Sreemantula, Krishna M Boini and Srinivas Nammi

    Citation: BMC Pharmacology 2004 4:30

    Content type: Research article

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  12. Palm olein oil (PO), obtained from refining of palm oil is rich in monounsaturated fatty acid and antioxidant vitamins and is widely used as oil in diet in many parts of the world including India. Palm oil has...

    Authors: Deepak Narang, Subeena Sood, Mathew Kadali Thomas, Amit Kumar Dinda and Subir Kumar Maulik

    Citation: BMC Pharmacology 2004 4:29

    Content type: Research article

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  13. Administration of the N-methyl-D-aspartate (NMDA) antagonist ketamine during the perinatal period can produce a variety of behavioral and neuroanatomical changes. Our laboratory has reported reliable changes i...

    Authors: G Andrew Mickley, Cynthia L Kenmuir, Colleen A McMullen, Alicia Snyder, Anna M Yocom, Deborah Likins-Fowler, Elizabeth L Valentine, Bettina Weber and Jaclyn M Biada

    Citation: BMC Pharmacology 2004 4:28

    Content type: Research article

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  14. Fluoxetine and olanzapine combination therapy is rapidly becoming an effective strategy for managing symptoms of treatment-resistant depression. Determining drug-drug interactions, drug metabolism and pharmaco...

    Authors: Jennifer A Perrone, Janet M Chabla, Brian H Hallas, Judith M Horowitz and German Torres

    Citation: BMC Pharmacology 2004 4:27

    Content type: Research article

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  15. Endogenous nitric oxide (NO) and carbon monoxide (CO) are generated by nitric oxide synthase and heme oxygenase, respectively. Like NO, CO has been accepted as an important cellular signaling molecule in biolo...

    Authors: Robert Kinobe, Yanbin Ji and Kanji Nakatsu

    Citation: BMC Pharmacology 2004 4:26

    Content type: Research article

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  16. The anti-inflammatory effects of proanthocyanidins (PACs), isolated from blackcurrant (Ribes nigrum L.) leaves, were analysed using carrageenin-induced paw oedema and carrageenin-induced pleurisy in rats.

    Authors: Nancy Garbacki, Monique Tits, Luc Angenot and Jacques Damas

    Citation: BMC Pharmacology 2004 4:25

    Content type: Research article

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  17. The activation of GABAB receptors in the ventral tegmental area (VTA) has been suggested to attenuate the rewarding properties of psychostimulants, including nicotine. However, the neurochemical mechanism that un...

    Authors: Diana Amantea and Norman G Bowery

    Citation: BMC Pharmacology 2004 4:24

    Content type: Research article

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  18. PPARγ agonists ameliorate insulin resistance and dyslipidemia in type 2 diabetic patients. Adiponectin possesses insulin sensitizing properties, and predicts insulin sensitivity of both glucose and lipid metab...

    Authors: Baichun Yang, Kathleen K Brown, Lihong Chen, Kevin M Carrick, Lisa G Clifton, Judi A McNulty, Deborah A Winegar, Jay C Strum, Stephen A Stimpson and Gregory L Pahel

    Citation: BMC Pharmacology 2004 4:23

    Content type: Research article

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  19. Psoriasis is a chronic inflammatory skin disease that can be successfully treated with a mixture of fumaric acid esters (FAE) formulated as enteric-coated tablets for oral use. These tablets consist of dimethy...

    Authors: Nicolle HR Litjens, Elisabeth van Strijen, Co van Gulpen, Herman Mattie, Jaap T van Dissel, H Bing Thio and Peter H Nibbering

    Citation: BMC Pharmacology 2004 4:22

    Content type: Research article

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