Volume 9 Supplement 1

4th International Conference of cGMP Generators, Effectors and Therapeutic Implications

Meeting abstracts

Regensburg, Germany19-21 June 2009

Page 3 of 3

Pharmacological preconditioning with the guanylate cyclase activator cinaciguat (BAY 58-2667) protects against reperfusion injury after cardiopulmonary bypass

Authors: Tamás Radovits, Sevil Korkmaz, Sivakkanan Loganathan, Johannes-Peter Stasch, Matthias Karck and Gábor Szabó

Citation: BMC Pharmacology 2009 9(Suppl 1):P56

Content type: Poster presentation Published on: 11 August 2009
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Nucleotidyl cyclase activity of recombinant soluble guanylyl cyclase

Authors: Kerstin Rauch, Johannes-Peter Stasch, Volkhard Kaever and Roland Seifert

Citation: BMC Pharmacology 2009 9(Suppl 1):P57

Content type: Poster presentation Published on: 11 August 2009
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The novel NO redox sibling, nitroxyl (HNO), prevents cardiomyocyte hypertrophy and superoxide generation via cGMP

Authors: Rebecca Ritchie, Jennifer Irvine, Swati Gossain, Jane Love, John Horowitz and Barbara Kemp-Harper

Citation: BMC Pharmacology 2009 9(Suppl 1):P58

Content type: Poster presentation Published on: 11 August 2009
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Antihypertrophic actions of NO-independent soluble guanylyl cyclase (sGC) ligands BAY 41-2272 and BAY 58-2667 in vitro

Authors: Rebecca Ritchie, Jennifer Irvine, Jane Love, John Horowitz, Johannes-Peter Stasch and Barbara Kemp-Harper

Citation: BMC Pharmacology 2009 9(Suppl 1):P59

Content type: Poster presentation Published on: 11 August 2009
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NO inhibits platelet apoptosis by cGMP-dependent and-independent pathways

Authors: Natalia Rukoyatkina, Ulrich Walter and Stepan Gambaryan

Citation: BMC Pharmacology 2009 9(Suppl 1):P60

Content type: Poster presentation Published on: 11 August 2009
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The neuronal PDE2A3 splice variant is targeted to membranes via dual acylation

Authors: Corina Russwurm, Georg Zoidl, Doris Koesling and Michael Russwurm

Citation: BMC Pharmacology 2009 9(Suppl 1):P61

Content type: Poster presentation Published on: 11 August 2009
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NO/cGMP signalling in platelets

Authors: Elisabeth Schinner and Jens Schlossmann

Citation: BMC Pharmacology 2009 9(Suppl 1):P62

Content type: Poster presentation Published on: 11 August 2009
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The degree of natriuretic peptide system activation in stable and high risk CHF characterized by increased cystatin C is not reflected in cGMP activation

Authors: John A Schirger, Horng H Chen, Josh Slusser, David Hodge, Denise Heublein, Alessandro Cataliotti, Sharon Sandberg and John C Burnett Jr

Citation: BMC Pharmacology 2009 9(Suppl 1):P63

Content type: Poster presentation Published on: 11 August 2009
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C-type natriuretic peptide is a bifurcation factor for sensory neurons

Authors: Hannes Schmidt, Agne Stonkute, René Jüttner, Doris Koesling, Andreas Friebe, Robert Feil, Franz Hofmann and Fritz G Rathjen

Citation: BMC Pharmacology 2009 9(Suppl 1):P64

Content type: Poster presentation Published on: 11 August 2009
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Quantitation of cyclic dinucleotides by reversed-phase LC-MS/MS

Authors: Christian Spangler, Roland Seifert and Volkhard Kaever

Citation: BMC Pharmacology 2009 9(Suppl 1):P65

Content type: Poster presentation Published on: 11 August 2009
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Sensitive assay for the detection of cyclic nucleotides by mass spectrometry

Authors: Corinna M Spangler, Bettina Wilhelm, Heike Burhenne, Kerstin Rauch, Roland Seifert and Volkhard Kaever

Citation: BMC Pharmacology 2009 9(Suppl 1):P66

Content type: Poster presentation Published on: 11 August 2009
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The role of cGMP-cGKI-signaling for duodenal bicarbonate secretion

Authors: Beate Spiessberger, Pascal Weinmeister, Franz Hofmann, Claudia Werner, Dieter Saur, Ursula Seidler, Wen Zheng, Jens Schlossmann and Robert Lukowski

Citation: BMC Pharmacology 2009 9(Suppl 1):P67

Content type: Poster presentation Published on: 11 August 2009
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Mechanisms of relaxant activity of BAY 41-2272 in rat tracheal smooth muscle in vitro

Authors: Haroldo AF Toque, Rafael P Morganti, Gilberto De Nucci and Edson Antunes

Citation: BMC Pharmacology 2009 9(Suppl 1):P68

Content type: Poster presentation Published on: 11 August 2009
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Blockade of CNG channels abrogates urethral relaxation induced by soluble guanylate cyclase activation

Authors: Domingo Triguero, Maria Sancho, Marta García-Flores and Ángeles García-Pascual

Citation: BMC Pharmacology 2009 9(Suppl 1):P69

Content type: Poster presentation Published on: 11 August 2009
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Is kynurenine a novel and important vasodilator in human septic shock?

Authors: Yutang Wang, Dechaboon Changsiri, Gavin McKenzie, Johannes-Peter Stasch, Michael Hahn, C Woolfe, D Rajbhandari, David S Celermajer and Roland Stocker

Citation: BMC Pharmacology 2009 9(Suppl 1):P70

Content type: Poster presentation Published on: 11 August 2009
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Stimulation of soluble guanylate cyclase accelerates renal recovery following relief of unilateral ureteral obstruction

Authors: Yingrui Wang-Rosenke, Dmytro Khadzhynov, Tanja Loof, Stephanie Krämer, Bogdan Iliev, Alice Mika, Hans H Neumayer and Harm Peters

Citation: BMC Pharmacology 2009 9(Suppl 1):P71

Content type: Poster presentation Published on: 11 August 2009
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Role of the general base Glu268 in nitroglycerin bioactivation and mechanism-based superoxide formation by aldehyde dehydrogenase-2

Authors: M Verena Wenzl, Matteo Beretta, Antonius CF Gorren, Pravas K Baral, Karl Gruber, Michael Russwurm, Doris Koesling, Kurt Schmidt and Bernd Mayer

Citation: BMC Pharmacology 2009 9(Suppl 1):P72

Content type: Poster presentation Published on: 11 August 2009
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Pharmacological characterization of receptor guanylyl cyclase reporter cell lines

Authors: Frank Wunder, Daniel Barufe, Annette Woermann and Markus Milde

Citation: BMC Pharmacology 2009 9(Suppl 1):P73

Content type: Poster presentation Published on: 11 August 2009
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Therapeutic potential of CNP for skeletal dysplasias

Authors: Akihiro Yasoda, Hidetomo Kitamura, Toshihito Fujii, Eri Kondo, Naoaki Murao, Masako Miura, Naotetsu Kanamoto, Yasato Komatsu, Hiroshi Arai and Kazuwa Nakao

Citation: BMC Pharmacology 2009 9(Suppl 1):P74

Content type: Poster presentation Published on: 11 August 2009
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Determination of new phosphorylation sites within natriuretic peptide receptors using mass spectrometric methods

Authors: Andrea R Yoder, Matthew D Stone, Tim Griffin and Lincoln R Potter

Citation: BMC Pharmacology 2009 9(Suppl 1):P75

Content type: Poster presentation Published on: 11 August 2009
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Possible identification of novel natriuretic peptide receptor phosphorylation sites by alanine/glutamate mutagenesis

Authors: Andrea R Yoder, Kathryn A Barbieri, Jerid W Robinson and Lincoln R Potter

Citation: BMC Pharmacology 2009 9(Suppl 1):P76

Content type: Poster presentation Published on: 11 August 2009
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Effect of exercise training on endothelium-dependent relaxing response and cGMP concentration in pulmonary artery from rats submitted to lung ischemia/reperfusion

Authors: Angelina Zanesco, Maria A Delbin, Ana PC Davel, Fernando R Bau, Fernanda BM Priviero, Luciana V Rossoni and Edson Antunes

Citation: BMC Pharmacology 2009 9(Suppl 1):P77

Content type: Poster presentation Published on: 11 August 2009
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L-arginine supplementation improves aortic vascular relaxation via NO-independent sGC/cGMP signaling in exercised rats

Authors: Angelina Zanesco, Fernanda MB Priviero, Julio A Rojas-Moscoso, Alexandre S Silva and Edson Antunes

Citation: BMC Pharmacology 2009 9(Suppl 1):P78

Content type: Poster presentation Published on: 11 August 2009
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Regulation of smooth muscle-specific gene expression by cGMP-dependent protein kinase

Authors: Tong Zhang, Raphaela Schwappacher, Shunhui Zhuang and Renate B Pilz

Citation: BMC Pharmacology 2009 9(Suppl 1):P79

Content type: Poster presentation Published on: 11 August 2009
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Regulation of soluble guanylyl cyclase by phosphorylation

Authors: Zongmin Zhou, Nazish Sayed, Anastasia Pyriochou, David Fulton, Annie Beuve and Andreas Papapetropoulos

Citation: BMC Pharmacology 2009 9(Suppl 1):P80

Content type: Poster presentation Published on: 11 August 2009
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4th International Conference of cGMP Generators, Effectors and Therapeutic Implications

Meeting abstracts

Pharmacological preconditioning with the guanylate cyclase activator cinaciguat (BAY 58-2667) protects against reperfusion injury after cardiopulmonary bypass

Nucleotidyl cyclase activity of recombinant soluble guanylyl cyclase

The novel NO redox sibling, nitroxyl (HNO), prevents cardiomyocyte hypertrophy and superoxide generation via cGMP

Antihypertrophic actions of NO-independent soluble guanylyl cyclase (sGC) ligands BAY 41-2272 and BAY 58-2667 in vitro

NO inhibits platelet apoptosis by cGMP-dependent and-independent pathways

The neuronal PDE2A3 splice variant is targeted to membranes via dual acylation

NO/cGMP signalling in platelets

The degree of natriuretic peptide system activation in stable and high risk CHF characterized by increased cystatin C is not reflected in cGMP activation

C-type natriuretic peptide is a bifurcation factor for sensory neurons

Quantitation of cyclic dinucleotides by reversed-phase LC-MS/MS

Sensitive assay for the detection of cyclic nucleotides by mass spectrometry

The role of cGMP-cGKI-signaling for duodenal bicarbonate secretion

Mechanisms of relaxant activity of BAY 41-2272 in rat tracheal smooth muscle in vitro

Blockade of CNG channels abrogates urethral relaxation induced by soluble guanylate cyclase activation

Is kynurenine a novel and important vasodilator in human septic shock?

Stimulation of soluble guanylate cyclase accelerates renal recovery following relief of unilateral ureteral obstruction

Role of the general base Glu268 in nitroglycerin bioactivation and mechanism-based superoxide formation by aldehyde dehydrogenase-2

Pharmacological characterization of receptor guanylyl cyclase reporter cell lines

Therapeutic potential of CNP for skeletal dysplasias

Determination of new phosphorylation sites within natriuretic peptide receptors using mass spectrometric methods

Possible identification of novel natriuretic peptide receptor phosphorylation sites by alanine/glutamate mutagenesis

Effect of exercise training on endothelium-dependent relaxing response and cGMP concentration in pulmonary artery from rats submitted to lung ischemia/reperfusion

L-arginine supplementation improves aortic vascular relaxation via NO-independent sGC/cGMP signaling in exercised rats

Regulation of smooth muscle-specific gene expression by cGMP-dependent protein kinase

Regulation of soluble guanylyl cyclase by phosphorylation

BMC Pharmacology