Figure 1From: A covalent peptide inhibitor of RGS4 identified in a focused one-bead, one compound library screenHit peptides in the FCPIA. Hit peptides from Roof, et al. 2008 were tested at 50 μM unless otherwise indicated for ability to disrupt the RGS4-Gαo interaction as described using 25 nM Gα o-Alexa Fluor-532 and 5 nM wild type RGS4-biotin (mean ± S.E.M., n ≥ 3) *p < 0.05, **p < 0.01, ***p < 0.001 compared to no peptide.Back to article page