Figure 3From: AICAR activates the pluripotency transcriptional network in embryonic stem cells and induces KLF4 and KLF2 expression in fibroblastsAICAR induces Klf4, Klf2 and Myc expression in fibroblasts. Murine embryonic fibroblasts were cultured in the presence or absence of AICAR for 48 h. AICAR induced upregulation of Klf4, Klf2 and Myc. Taqman real time quantitative PCR. N = 3. Graphs represent average +/- SEM. *** = P < 0.0001, ** = P < 0.001, * = P < 0.05.Back to article page