Figure 6From: Differential regulation of muscarinic M1 receptors by orthosteric and allosteric ligandsInternalization of muscarinic M 1 receptors by analogues of AC-260584. HEK-293 cells expressing EE-hM1 were treated with 1 μM of each ligand and localization of EE-hM1 receptors were visualized using confocal microscopy. Images are from a representative experiment repeated 2-3 times with similar results.Back to article page