Figure 6

Charge neutralization at E¹⁷² does not alter the rate of modification M⁴⁰C by MTSEA. Mean values for second-order modification rate constants for M⁴⁰C (left, data from Fig. 3) compared to those obtained in receptors containing the E¹⁷²Q mutation (M⁴⁰C/E¹⁷²Q). *Rates were significantly different from control (P < 0.05). See Table 2 for summary, including (n) for each condition.