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Figure 5 | BMC Pharmacology

Figure 5

From: Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells

Figure 5

Forskolin-stimulated 3H-cAMP accumulation in CHO-H3-SPAP cells in response to a) histamine, b) immethridine, c) impentamine d) proxyfan and e) burimamide in the absence and presence of 10 nM clobenpropit. Bars show basal 3H-cAMP accumulation, that in response to 10 μM forskolin alone and that in response to 10 nM clobenpropit in the presence of 10 μM forskolin. Data points are mean ± s.e.m. of triplicate values from single experiments that are representative of a) 5, b) 5, c) 4, d) 5 and e) 4 separate experiments.

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