Figure 4

CRE-SPAP production in forskolin-stimulated CHO-H3-SPAP cells in response to a) N-α-methylhistamine, b) R-α-methylhistamine, c) imetit, d) immepip and e) proxyfan in the absence and presence of 100 nM VUF 5681. Bars show basal CRE-SPAP production and that in response to 4 μM forskolin alone and 100 nM VUF 5681 in the presence of 4 μM forskolin. Data points are mean ± s.e.m. of triplicate values from a single experiment and are representative of a) 4, b) 4, c) 4, d) 3 and e) 3 separate experiments.