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Figure 2 | BMC Pharmacology

Figure 2

From: Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells

Figure 2

CRE-SPAP production in forskolin-stimulated CHO-H3-SPAP cells in response to a) histamine, b) R-α-methylhistamine, c) imetit, d) immepip and e) proxyfan in the absence and presence of 10 nM, 100 nM or 1000 nM clobenpropit. Bars show basal CRE-SPAP production and that in response to 4 μM forskolin alone, and 10 nM, 100 nM or 1000 nM clobenpropit in the presence of 4 μM forskolin. Data points are mean ± s.e.m. of triplicate values from a single experiment and are representative of a) 3, b) 4, c) 4, d) 4 and e) 4 separate experiments.

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