Table 2 Phenotype of C57BL/6 DIO mice
From: RU486 did not exacerbate cytokine release in mice challenged with LPS nor in db/db mice
Normal diet controls | DIO mice | |
|---|---|---|
Body weight (g) | 28.7 ± 0.3 | 44.6 ± 0.6** |
Blood | ||
Glucose (mg/dL) | 121 ± 3 | 160 ± 6* |
HbA1c (%) | 3.6 ± 0.2 | 3.5 ± 0.3 |
Serum | ||
Glucose (mg/dL) | 225 ± 15** | 344 ± 22* |
Insulin (ng/ml) | 0.45 ± 0.06 | 5.07 ± 1.03** |
Total cholesterol (mg/dL) | 67.0 ± 3.3 | 223.0 ± 3.1** |
Triglycerides (mg/dL) | 93.0 ± 14.6 | 138.0 ± 9.8* |
FFA (mEq/L) | 0.35 ± 0.03 | 0.47 ± 0.02* |
IL-6 (pg/ml) | 191.2 ± 86.7 | 243.2 ± 144.7 |
TNFα(pg/ml) | 24.0 ± 1.1 | 35.6 ± 2.4* |
Corticosterone (ng/ml) | 310 ± 30 | 380 ± 86 |
ACTH (ng/ml) | 2.3 ± 0.2 | 3.3 ± 1.0 |