Figure 1From: RU486 did not exacerbate cytokine release in mice challenged with LPS nor in db/db miceEffects of RU486 (oral, BID, 10 days) on blood glucose (a), liver genes of PEPCK (b) and G6Pase (c), and serum IL-6 and MCP-1 (d), corticosterone (e), and ACTH (f) in db/db mice. Lean-V: lean litter mates treated with vehicle. db/db-V: db/db mice treated with Vehicle. db/db-RU 2.5: db/db mice treated with RU486 2.5 mg/kg. db/db-RU 7: db/db mice treated with RU486 7 mg/kg. db/db-RU 20: db/db mice treated with RU486 20 mg/kg. db/db-RU 50: db/db mice treated with RU486 50 mg/kg. Serum corticosterone and ACTH were presented as ng/ml. PEPCK and G6Pase were normalized with cyclophilin.Back to article page