Figure 8From: Inhibition of 11βHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAy miceEffects of BVT2733 on (A) adiponectin and (B) glycosylated hemoglobin in male KKAy mice. Animals were treated with vehicle (white circles), BVT2733 30 mg/kg (black circles), BVT2733 100 mg/kg (white squares), BVT2733 (black squares) or 5 mg/kg rosiglitazone (white triangles) for 8 days and plasma adiponectin and HbA1c were measured. * p < 0.05, ** p < 0.01, *** p < 0.001 versus vehicle, n = 9 per group.Back to article page